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UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL KULIT BATANG SUKUN (Artocarpus altil…
The bark of breadfruit (Artocarpus altilis) contains secondary metabolites such as flavonoids and phenolics that have antioxidant potential. This study aimed to determine the effect of breadfruit bark ethanol extract (EEKBS) on Wistar rats induced with gentamicin and piroxicam, causing oxidative stress. A total of 30 test animals were divided into 6 treatment groups, namely the normal group (Na…
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- xix, 122 hlm.; ilus.; tab.; 29 cm.
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- T1929062026
STUDI KOMPARATIF TERAPI KOMBINASI TERHADAP PERBAIKAN FUNGSI FISIK DAN INTENSI…
Low back pain (LBP) is one of commonly encountered musculoskeletal disorders and may lead to physical function limitations and decreased quality of life. Pharmacological therapy commonly used in the management of LBP includes combinations of non-steroidal anti-inflammatory drugs (NSAIDs) with Paracetamol or muscle relaxants as adjuvant therapy. This study aimed to analyze the differences in phy…
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- xiv, 170 hlm.; ilus.; tab.; 29 cm.
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- T1926782026
UJI AKTIVITAS ANTIINFLAMASI DAN TOKSISITAS AKUT EKSTRAK ETANOL HERBA SIRIH CI…
Synthetic anti-inflammatory drugs are associated with the risk of serious adverse effects, highlighting the need for safer alternatives. Pepper elder (Peperomia pellucida L.) has been reported to exhibit anti-inflammatory activity in male rats; however, studies in female rats and data regarding its safety remain limited. This study aimed to evaluate the anti-inflammatory activity in female Wist…
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- xi, 174 hlm.; ilus.; 29 cm
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- T1921942026
EVALUASI RASIONALITAS TERAPI PASIEN DEMAM TIFOID DI INSTALASI RAWAT INAP RSI …
Typhoid fever is a common infectious disease in Indonesia and may lead to serious complications if not managed appropriately. This study aimed to evaluate the rationality of drug therapy in hospitalized typhoid fever patients based on eight parameters of appropriateness. This research employed a prospective descriptive analytical design. Data were obtained from patients’ medical records and d…
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- x, 68 hlm.; ilus.; tab.; 29 cm
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- T1937302026
ANALISIS POLA PERESEPAN OBAT DAN KESESUAIAN PEDOMAN TERAPI PASIEN DEWASA ISPA…
Acute Respiratory Infection (ARI) is one of the most common diseases encountered among adult patients in healthcare facilities. This study aims to evaluate drug prescribing patterns and analyze their compliance with the Ministry of Health of the Republic of Indonesia's therapy guidelines for adult ARI patients at the Sukarami Public Health Center (Puskesmas) in Palembang. This study employed a …
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- xviii, 52 hlm.; ilus.; tab.; 29 cm
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- T1934932026
UJI AKTIVITAS ANTIDEPRESAN EKSTRAK ETANOL KULIT BATANG SUKUN (Artocarpus alti…
Ethanol extract of breadfruit (Artocarpus altilis) stem bark is known to contain flavonoid compounds suspected to have potential as an antidepressant agent. This study was conducted to determine the effect and optimal concentration of the ethanol extract of breandruit stem bark for depression treatment. The test animals were divided into six groups: normal group (Na-CMC), negative group (Na-CMC…
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- xxi, 57 hlm.; ilus.; tab.; 29 cm
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- T1937192026
STUDI IN SILICO PENELURUSAN AGEN TERAPI DIABETES MELITUS BERBASIS EKSTRAK DAU…
The number of diabetes mellitus cases continues to increase each year. Antidiabetic drugs are essential for individuals with diabetes, particularly type 2, to control blood glucose levels. However, commonly used modern antidiabetic drugs are often associated with adverse side effects. Therefore, natural products such as karamunting leaves (Rhodomyrtus tomentosa (Aiton) Hassk.) have been investi…
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- xix, 236 hlm.; ilus.; 29 cm
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- T1907222026
STUDI IN SILICO PENELURUSAN AGEN TERAPI DIABETES MELITUS DARI SENYAWA BIOAKTI…
Diabetes melitus is a chronic disease with a steadily increasing global prevalence, posing a significant concern in public health. This metabolic disorder is characterized by elevated blood glucose levels, which may lead to long-term complications if not managed properly. Conventional pharmacological therapies are commonly used to regulate glucose levels, but long-term use carries a risk of ser…
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- xix, 344 hlm.; ilus.; 29 cm
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- T1904422026
FORMULASI NANOPARTIKEL PERAK-MAGNETIT MENGGUNAKAN METODE GREEN SYNTHESIS DENG…
Thrombosis is a condition in which a blood clot (thrombus) forms in a blood vessel. Treatment involves antithrombotic agents such as anticoagulants, and researchers developed silver-magnetite nanoparticles (Ag-Fe₃O₄) using a green synthesis method using robusta coffee bean extract (Coffea canephora) containing chlorogenic acid as a natural reducing, stabilizing, and thrombolytic agent. The …
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- xx, 153 hlm.; ilus.; tab.; 29 cm.
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- T1842542025
GREEN SYNTHESIS NANOPARTIKEL BESI OKSIDA EKSTRAK JARAH GAMBIR (UNCARIA GAMBIR…
Thrombosis is a leading global cause of cardiovascular diseases. While anticoagulants, antiplatelet agents, and thrombolytic therapies are the standard clinical treatments, iron oxide nanoparticles offer an alternative approach due to their ability to accumulate at sites of inflammation, such as thrombi and atherosclerotic plaques. These nanoparticles can act as photothermal agents, absorbing l…
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- xix, 99 hlm.; ilus.; tab.; 29 cm.
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- T1841362025
KARAKTERISASI LIPOSOM PHOTOSENSITIZER PEMBAWA EKSTRAK KASAR NANAS (Ananas com…
Thrombosis is a condition that occurs due to an imbalance in the hemostasis system characterized by the formation of a blood clot (thrombus) in the blood vessel wall so that it can cause ischemic stroke disease. The anti-thrombotic drugs commonly used are thrombolytics. These drugs contain fibrinolytic enzymes such as protease enzymes. Pineapple (Ananas comosus (L.) Merr) is known to have an an…
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- xix, 98 hlm.; ilus.; tab.; 29 cm.
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- T1842462025
OPTIMASI GREEN SYNTHESIS NANOPARTIKEL Ag-Fe3O4 MENGGUNAKAN EKSTRAK AIR BUNGA …
Thrombosis caused by blood clot formation can lead to serious complications. Conventional therapies carry a risk of bleeding, making photothermal therapy based on optical-magnetic nanoparticles such as AgNO₃ and Fe₃O₄ a safer alternative. These nanoparticles are synthesized via green synthesis using butterfly pea flower (Clitoria ternatea L.) extract, which contains flavonoids and anthocy…
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- xx, 175 hlm.; ilus.; tab.; 29 cm.
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- T1841272025
EFEK TERATOGENIK FRAKSI ETIL ASETAT DAUN MELINJO (Gnetum gnemon L.) PADA FETU…
One of the special toxicity tests is the teratogenic test which is carried out to obtain information on the presence of fetal abnormalities that occur due to the administration of test preparations during the formation of fetal organs (organogenesis period) and to complete safety data from the melinjo plant. The doses given were 69.48, 104.22, 138.96 and 173.7 mg/kgBW. The administration of the…
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- xvi, 107 hlm.; ilus.; 29 cm
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- T1590302024
EFEK TERATOGENIK FRAKSI ETANOL DAUN KERSEN (Muntingia calabura L.) PADA FETUS…
Kersen leaves (Muntingia Calabura L) contain secondary metabolite compounds alkaloids, flavonoids and tanins. The use of herbal medicine during pregnancy needs to be considered because the drug can cross the placenta so that it can cause teratogenic effects on the fetus. Teratogenic toxicity research on the ethanol fraction of kersen leaves (Muntingia Calabura L) has been conducted to determine…
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- xiv, 165 hlm.; ilus.; 29 cm
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- T1590292024
FORMULASI DAN EVALUASI SEDIAAN ACNE PATCH TRANSDERMAL EKSTRAK ETANOL DAUN CAB…
Acne is a condition characterized by the accumulation of sebum from sebaceous glands in the skin layers, which often stimulates the growth of acne-causing bacteria, such as Staphylococcus aureus. Acne treatment can be performed using acne patches; however, commercial acne patches are only capable of absorbing sebum without providing antibacterial activity. This study aimed to enhance therapeuti…
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- xvi, 107 hlm.; ilus.; tab.; 29 cm.
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- T1861272025
FORMULASI DAN UJI ANTIOKSIDAN ORALLY DISSOLVING FILM EKSTRAK ETANOL BUNGA K…
Bunga kecombrang (Etlingera elatior) dikenal sebagai bunga khas Asia tenggara famili Zingiberaceae dengan warna merah menyala dan bau khas. Pemanfaatan sediaan orally dissolving film (ODF) dapat menetralisir rasa asam pada bunga kecombrang. Variasi konsentrasi ekstrak etanol bunga kecombrang 0,5%, 0,6%, 0,7%. Evalusi sediaan untuk menentukan formula terbaik meliputi organoleptis, ketebalan, bob…
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- xiii, 87 hlm.; ilus.; 29 cm
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- T1598302024
ISOLASI MINYAK ATSIRI PADA TANAMAN GAMBIR (Uncaria gambir Roxb) DAN INDETIFIK…
Essential oil is one of the non-oil and gas export commodities, gambir is one of the sap-producing plants used for industrial and pharmaceutical purposes, how much gambir essential oil and yield obtained and what components are contained in gambir essential oil, and how much yield is obtained, knowing the components contained in gambir essential oil (Uncaria Gambir Roxb), the research method us…
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- xiv, 58 hlm.; ilus.; 29 cm
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- T1595682024
ANALISIS DRUG RELATED PROBLEMS (DRPs) PADA PASIEN HIPERLIPIDEMIA DENGAN KOMPL…
Hyperlipidemia is a metabolic disorder that acts as a major risk factor for cardiovascular disease. This condition is often accompanied by various complications such as hypertension, diabetes mellitus, and ischemic heart disease, which causes higher complexity of therapy. The complexity of treatment in hyperlipidemia patients increases the potential for Drug-Related Problems (DRPs), which can a…
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- xxvii, 115 hlm.; ilus.; tab.; 29 cm.
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- T1859012025
UJI STIMULASI PROBIOTIK Bifidobacterium longum DENGAN EKSTRAK ETANOL DAUN PUT…
This study aims to evaluate the potential of ethanol extract of putat leaves (Barringtonia acutangula) in stimulating the growth of probiotic Bifidobacterium longum and test its ability to inhibit the growth of pathogenic Escherichia coli bacteria. Bifidobacterium longum is one of the lactic acid bacteria that are beneficial for human gut health, while E. coli bacteria are known as opportunisti…
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- xx, 128 hlm.; ilus.; tab, 29 cm
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- T1806912025
FORMULASI SEDIAAN SPANSULE EKSTRAK ETANOL DAUN PUTAT (Barringtonia acutangula…
Diarrhea caused by Escherichia coli infections remains a significant public health problem in developing countries, including Indonesia. Overuse of antibiotics can lead to resistance, so alternatives are needed. Putat leaves (Barringtonia acutangula) contain the flavonoid quercetin, which has prebiotic and antibacterial potential. This study aims to investigate the effect of putat leaf extract …
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- xvii, 64 hlm.; ilus.; tab.; 29 cm.
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- T1806002025
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAN FRAKSI HERBA SIRIH CINA (peperomia pell…
Chinese betel leaf (peperomia pellucida) contains secondary metabolite compounds such as flavonoids and terpenoids that have potential as antioxidants. This study aims to determine the effect of giving extracts and fractions of Chinese betel herb invivo on male Wistar rats induced oxidative stress by carbon tetrachloride (CCl4). The 30 test animals were divided into 6 treatment groups, namely t…
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- xvi, 52 hlm.; ilus.; tab, 29 cm
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- T1795672025
UJI AKTIVITAS ANTIDEPRESAN EKSTRAK ETANOL DAUN AKASIA (acacia mangim wild) TE…
Acacia leaves (Acacia Mangium Wild) contain secondary metabolite compounds of flavonoids in the form of quercetin which have the potential as antidepressants. This study aims to determine the effect of giving ethanol extract of acacia leaves and its effective dose on antidepressant activity. This study used 30 test animals which were divided into 6 groups, namely, the normal group (1 NaCMC with…
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- xvi, 48 hlm.; ilus.; tab, 29 cm
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- T1802672025
EVALUASI PENGARUH WAKTU TUNGGU RESEP TERHADAP TINGKAT KEPUASAN PASIEN RAWAT J…
Pharmaceutical services are an important aspect of health facilities that directly affect patient satisfaction, one such service is prescription services. Patients often complain about waiting time for prescription services because it impacts their experience obtaining health services. The objective of this study evaluates how waiting time towards prescription services affects outpatient satisf…
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- xvi, 125 hlm.; ilus.; tab, 29 cm
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- T1806392025
STUDI IN SILICO EKSTRAK BUNGA KECOMBRANG (Etlingera Elatior) SEBAGAI ANTIBAKT…
Staphylococcus aureus infection is caused by a bacterium that colonizes various organs in the human body, particularly the upper respiratory tract, including the skin, nasal cavity, axilla, and inguinal area. The emergence of antibiotic-resistant S. aureus, known as MRSA and VRSA, presents a significant challenge in the treatment of such infections. Natural products, such as the torch ginger fl…
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- xvii, 64 hlm.; ilus.; tab, 29 cm
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- T1805082025
UJI TOKSISITAS SUBKRONIS EKSTRAK ETANOL DAUN KENCANA UNGU (Ruellia tuberosa L…
Daun kencana ungu (Ruellia tuberosa L.) merupakan salah satu tanaman yang dimanfaatkan secara luas sebagai obat tradisional. Daun kencana ungu memiliki aktivitas farmakologis sebagai antihiperglikemia, antidiabetes, dan antihipertensi. Penelitian ini dilakukan dengan tujuan untuk mengetahui toksisitas subkronis ekstrak etanol daun kencana ungu terhadap tikus putih jantan galur Wistar. Pada pene…
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- xxi, 107 hlm.; ilus.; 29 cm
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- T1426592024
UJI DAYA ANTIOKSIDAN EKSTRAK DAN FRAKSI-FRAKSI PADA TANAMAN PALIASA (Kleinhov…
Paliasa (Kleinhovia hospita L.) belongs to Malvaceae family with high potential as a medicinal plant because it contains flavonoids,tannins,saponins, steroids and phenolic compounds. This study aims to measure total phenolic content and antioxidant power in extracts and fractions of stem bark, leaves, and root bark of Paliasa and the correlation between antioxidant and total phenolic. Testing t…
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- xviii, 132 hlm.; ilus.; 29 cm
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- T1430042024
OPTIMASI DAN UJI AKTIVITAS ANTIBAKTERI TRANSFERSOM FRAKSI ETIL ASETAT DAUN SI…
Daun singkong (Manihot esculenta Crantz.) terbukti sebagai antibakteri karena kandungan senyawa rutin yang tinggi. Transfersom mampu berpenetrasi melintasi stratum korneum untuk meningkatkan efek antibakteri senyawa rutin pada fraksi etil asetat daun singkong dengan hidrofilisitasnya. Penelitian ini bertujuan untuk mengoptimalkan formula transfersom fraksi etil asetat daun singkong dengan varia…
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- xx, 135 hlm.; ilus.; 29 cm
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- T1412992024
FORMULASI DAN UJIAKTIVITAS ANTIBAKTERI TRANSDERMAL PATCH FRAKSI ETIL ASETAT D…
Transdermal patch was chosen to manage the delivery system of the antibacterial compound in cassava leaves, which is rutin, that is hydrophilic. Plasticizer is one of the additional ingredients of transdermal patches that can maintain the bioavailability of a drug. Transdermal patch formulation with active cassava leaf ethyl acetate fraction ingredients and 3 variations of PEG-400 concentration…
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- xix, 118 hlm.; ilus.; 29 cm
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- T1421242024
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAN FRAKSI DAUN GELAM (MELALEUCA LEU…
Free radicals are dangerous because they can cause degenerative disease. Free radicals can be neutralized by antioxidants. Plants that has potential as an antioxidant is gelam (Melaleuca leucadendra (L.) L.). Gelam leaves contain phenolics, flavonoids, steroids, triterpenoids, tannins, and saponins that have pharmacological activity as antioxidants. The study aimed to determine the characterist…
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- xxii, 179 hlm.; ilus.; 29 cm
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- T1416672024
FORMULASI DISPERSI PADAT IBUPROFEN DENGAN NATRIUM ALGINAT DAN VARIASI KITOSAN…
Ibuprofen is included in the Biopharmaceutical Classification System (BCS) Class II, namely drugs with irregular, slow and incomplete absorption properties. The combination of chitosan polymer with sodium alginate will increase the solubility of ibuprofen without causing systemic toxicity. Making a solid dispersion of ibuprofen using the co-grinding technique is carried out with the aim of redu…
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- xvi, 88 hlm.; ilus.; 29 cm
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- T1422962024
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