Background Elderly individuals represent a population with a high potential for a decline in the quantity and quality of skeletal muscles, a condition known as sarcopenia. Muscle quantity refers to the reduction in muscle mass, while muscle quality can be assessed through muscle strength and physical performance as age advances. Sarcopenia significantly reduces the ability to perform daily func…
Background: The presence of a malignant pleural effusion (MPE) indicates advanced stage in malignancy, which severely compromises in a poor prognosis. The LENT score has been developed as a prognostic tool for MPE, yet its association with pleural effusion progression and six-month survival has not been thoroughly evaluated, particularly in Indonesia. Methods: This prospective cohort study incl…
Background: Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia resulting from impaired insulin secretion or insulin resistance, with chronic low-grade inflammation playing a role in its pathogenesis. Diacerein has anti-inflammatory effects and improves insulin sensitivity; however, clinical evidence in Indonesia remains limited. Objective: To evaluate the effect of adding diacere…
Background: Acute Coronary Syndrome (ACS) is one of the leading causes of mortality and hospitalization due to cardiovascular disease. Variations in patient characteristics and the presence of metabolic risk factors may influence the occurrence and prognosis of ACS. Therefore, understanding the profile of ACS patient characteristics is essential as a basis for preventive planning and clinical s…
Background: STEMI is an acute condition caused by obstruction of blood flow to the heart, leading to cardiomyocyte necrosis. This process begins with the formation of atherosclerotic plaques that cause total occlusion of the coronary artery lumen, resulting in myocardial ischemia. When transmural ischemia lasts for 20–40 minutes, cardiomyocyte necrosis occurs. Methods: This study aimed to des…
Background: Type 2 Diabetes Mellitus (T2DM) was a chronic metabolic disease with an increasing prevalence, accompanied by hepatic complications such as Metabolic Dysfunction–Associated Fatty Liver Disease (MAFLD). The duration of T2DM affected the severity of metabolic disturbances, insulin resistance, and hepatic fat accumulation. However, data on the incidence of MAFLD at RSUP Dr. Mohammad …
Background. Low back pain (LBP) is one of the most common musculoskeletal complaints and can adversely affect physical function, quality of life, and patient productivity. Vitamin D deficiency, assessed through serum 25-hydroxyvitamin D (25-OH D) levels, plays a role in pain modulation, muscle function, and inflammatory responses, and is suspected to be associated with LBP occurrence. This stud…
Urothelial carcinoma is the most common malignancy of the urinary tract and exhibits a wide range of clinicopathological characteristics that influence prognosis and patient management. Local data regarding the clinicopathological characteristics of urothelial carcinoma in Palembang remain limited; therefore, this study was conducted to provide a more representative overview. This study was a d…
Background: Chronic Kidney Disease (CKD) is a progressive condition that requires long-term hemodialysis treatment. Hemodialysis results are greatly influenced by vascular access, especially Arteriovenous Shunt (AV Shunt) as permanent access and Double Lumen Catheter (CDL) as temporary access. The difference between the patient's characteristics and the clinical condition is often a factor in t…
Background: Bone marrow trephine biopsy is an essential diagnostic procedure for hematological diseases through assessment of morphology, fibrosis, cellularity, and tumor involvement. Since 2023, Dr. Mohammad Hoesin General Hospital Palembang has routinely performed bone marrow biopsies; however, clinicohistopathological data remain limited. This study aimed to describe the bone marrow clinicoh…
Background: Coronary Artery Bypass Graft (CABG) is a myocardial revascularization procedure aimed at restoring blood flow to the heart in patients with coronary artery disease. Postoperative evaluation of functional capacity is important to assess the effectiveness of cardiac recovery, particularly during phase I of cardiac rehabilitation. The Six-Minute Walk Test (6MWT) is a simple and safe me…
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype, with 150,000 new cases yearly. Roughly 40% of patients who receive rituximab in addition to vincristine, cyclophosphamide, doxorubicin, and prednisone treatment have primary refractory disease or recurrence. Although the Ann Arbor stage could determine DLBCL prognosis, new biomarkers are needed to stratify patient pro…
Background: Sarcopenia is a condition characterized by a decrease in muscle mass accompanied by a reduction in muscle strength and/or physical performance, which frequently occurs in older adults and leads to an increased risk of falls, dependency, cognitive and cardiopulmonary function decline, lower quality of life, mortality, and high healthcare costs. Calf circumference is recommended as a …
Background: Morbus Hansen (MH), also known as leprosy, is a chronic infectious disease caused by Mycobacterium leprae that primarily affects the skin and peripheral nerves. Despite global elimination efforts, MH remains a public health problem in Indonesia. Histopathological examination plays an essential role in establishing the diagnosis and determining the disease spectrum. This study aimed …
Background: Anemia is a common health problem among adolescent girls and can lead to decreased productivity, learning concentration, and academic performance. Medical students are expected to have good knowledge and attitudes toward anemia prevention; however, such understanding is not always reflected in preventive behaviors. Objective: This study aimed to determine the relationship between kn…
Background: The use of contact lenses continues to increase among university students, both for cosmetic purposes and refractive correction. However, improper usage behavior may increase the risk of complications, particularly when hygiene and wearing duration are not adequately managed. This study aimed to describe the compliance level regarding contact lens use among medical students at the F…
Background: Disorders of Sexual Development (DSD) is a congenital condition with a prevalence of 1:4,500–5,500 live births that can result in ambiguous genitalia and endocrine emergencies. External genitalia examination in newborns is often not comprehensive, risking sex assignment errors and diagnostic delays. This study aims to provide an overview of external genitalia features in pediatric…
Background: Leukemia is a hematopoietic malignancy characterized by abnormal leukocyte production in the bone marrow. The mortality and incidence rates of children with leukemia are the highest among all childhood cancers. One type of leukemia is acute myeloid leukemia (AML). About 20% of AML cases occur in children. The outcomes of children with AML may be influenced by several factors. Object…
Background. Overcrowded, humid, and unhygienic prison environments increase the risk of skin diseases among inmates. Epidemiological data on skin diseases in Indonesian prisons are still limited; therefore, this study aims to describe the pattern of skin diseases among inmates at the Class IIA Women’s Penitentiary in Palembang. Methods. This study was an analytical observational study with a …
Background: Nutritional problems among preschool-aged children remain a public health concern because they affect children’s growth and development. The Free Nutritious Meal Program (Makan Bergizi Gratis, MBG) is a school-based nutrition intervention initiated by the government to improve the quality of children’s dietary intake. However, data on changes in the anthropometric status of kind…
Latar Belakang. Lansia mengalami deteriorasi progresif fungsi fisiologis yang dapat meningkatkan risiko penyakit. Depresi dan gangguan nutrisi, dua masalah yang sering ditemukan pada lansia, dapat saling memengaruhi dan memperburuk kondisi kesehatan dan kualitas hidup lansia. Penelitian ini bertujuan untuk menganalisis korelasi antara gejala depresi dan status nutrisi pada pasien lansia. Metode…
Background: Sinonasal lesions are disorders of the nasal cavity and paranasal sinuses that include both neoplastic and non-neoplastic conditions. The wide variation in lesion types and differences in characteristics by age and sex make analysis of sinonasal case patterns important to support appropriate management. This study aimed to determine the clinicohistopathological characteristics of si…
Background. Steroid-resistant nephrotic syndrome (SRNS) represents a subtype of nephrotic syndrome associated with less favorable clinical outcomes compared to its steroid-sensitive counterpart. Despite its relatively low incidence, SRNS plays a substantial role in accelerating the progression toward chronic kidney disease and, ultimately, end-stage renal failure. In the Indonesian context, esp…
Background: Maternal Separation (MS) is a condition in which the mother and offspring are separated during the early stages of life, a critical period for the formation of physiological and psychological systems. This separation may induce stress that affects the Hypothalamus–Pituitary–Adrenal (HPA) axis, increases corticosterone levels, and alters brain structures such as the amygdala and …
Background. Neurofeedback therapy is a non-pharmacological approach that trains patients to regulate their brain activity through an EEG-based feedback system. This method has been applied to support neurological recovery in conditions such as stroke, epilepsy, and sleep disorders. However, its clinical implementation in Indonesia remains limited. This study aimed to describe the characteristic…
Background. Chronic cervicitis is a condition characterized by inflammation of the cervix lasting for more than three months and is frequently found in women of reproductive age. This condition can be caused by microbial infections, trauma, or other non-infectious factors. This study aims to describe the clinical cytopathological characteristics of patients with chronic cervicitis at RSUP Dr. M…
Background. Tension-Type Headache (TTH) is one of the most common primary headaches among young adults, especially medical students who are often exposed to intense academic pressure and long hours of gadget use. Digital devices play an important role in daily learning activities, yet prolonged screen time may contribute to physical complaints, including TTH. This study aimed to explore whether…
Background: Hyperuricemia is a condition associated with increased systemic inflammatory responses, characterized by elevated levels of tumor necrosis factor alpha (TNF-α) and uric acid. Allopurinol is one of the first-line treatments for hyperuricemia. Cherry leaf (Muntingia calabura L.) is known to contain flavonoids with anti-inflammatory and antihyperuricemic activities. Methods: An in viv…
Background: Retinoblastoma is the most common intraocular malignancy in children and remains associated with high mortality in developing countries due to delayed diagnosis and limited access to care. Epidemiological data in Indonesia, especially in Palembang, are limited. This study aimed to describe the prevalence and characteristics of retinoblastoma patients at Mohammad Hoesin General Hospi…
Background: Mitral Valve Replacement surgery is the surgical replacement of the mitral valve with an artificial valve. Clinical informations regarding mitral valve replacement surgery are needed to help predict complications and mortality after surgery. This study aims to determine the profile of patients undergoing Mitral Valve Replacement surgery at Dr. Mohammad Hoesin General Hospital Palemb…