EVALUASI RASIONALITAS TERAPI PASIEN DEMAM TIFOID DI INSTALASI RAWAT INAP RSI …

Typhoid fever is a common infectious disease in Indonesia and may lead to serious complications if not managed appropriately. This study aimed to evaluate the rationality of drug therapy in hospitalized typhoid fever patients based on eight parameters of appropriateness. This research employed a prospective descriptive analytical design. Data were obtained from patients’ medical records and d…

ANALISIS POLA PERESEPAN OBAT DAN KESESUAIAN PEDOMAN TERAPI PASIEN DEWASA ISPA…

Acute Respiratory Infection (ARI) is one of the most common diseases encountered among adult patients in healthcare facilities. This study aims to evaluate drug prescribing patterns and analyze their compliance with the Ministry of Health of the Republic of Indonesia's therapy guidelines for adult ARI patients at the Sukarami Public Health Center (Puskesmas) in Palembang. This study employed a …

UJI AKTIVITAS ANTIDEPRESAN EKSTRAK ETANOL KULIT BATANG SUKUN (Artocarpus alti…

Ethanol extract of breadfruit (Artocarpus altilis) stem bark is known to contain flavonoid compounds suspected to have potential as an antidepressant agent. This study was conducted to determine the effect and optimal concentration of the ethanol extract of breandruit stem bark for depression treatment. The test animals were divided into six groups: normal group (Na-CMC), negative group (Na-CMC…

STUDI IN SILICO PENELURUSAN AGEN TERAPI DIABETES MELITUS BERBASIS EKSTRAK DAU…

The number of diabetes mellitus cases continues to increase each year. Antidiabetic drugs are essential for individuals with diabetes, particularly type 2, to control blood glucose levels. However, commonly used modern antidiabetic drugs are often associated with adverse side effects. Therefore, natural products such as karamunting leaves (Rhodomyrtus tomentosa (Aiton) Hassk.) have been investi…

MODEL INVENTORI BARANG FARMASI YANG DETERIORATING PADA TINGKAT PERMINTAAN MEN…

In this study, a deteriorating inventory model of pharmaceutical goods with a demand level using a cosine function that considers the storage level is developed. The mathematical model formulation in this research is assisted by WolframAlpha software while the numerical calculation uses the help of Google Colab software. The results showed that the sensitivity analysis carried out affected the …

STUDI IN SILICO PENELURUSAN AGEN TERAPI DIABETES MELITUS DARI SENYAWA BIOAKTI…

Diabetes melitus is a chronic disease with a steadily increasing global prevalence, posing a significant concern in public health. This metabolic disorder is characterized by elevated blood glucose levels, which may lead to long-term complications if not managed properly. Conventional pharmacological therapies are commonly used to regulate glucose levels, but long-term use carries a risk of ser…

FORMULASI KRIM TABIR SURYA EKSTRAK ETANOL DAN FRAKSI DAUN SAMAK (SYZYGIUM URC…

Sun exposure can cause damage to the skin due to ultra violet (UV) radiation. Excessive and prolonged exposure to sunlight can damage the skin layer and can cause negative health effects Additional protection is needed to reduce the transmission of UV rays to the skin and is known as a sunscreen agent. Samak leaf (Syzygium urceolatum (Korth.) Merr. & L.M.Perry) has the potential as a sunscreen …

UJI AKTIVITAS DIURETIK FRAKSI ETIL ASETAT DAUN GAMAL (Gliricidia sepium) TERH…

Hypertension provides a major risk factor for cardiovascular and kidney disease. One of a therapy that used to treat a hypertension is diuretics. Gamal (Gliricidia sepium)contains flavonoid compounds which have diuretic effect. This study aims to determined activity of ethyl acetate fraction of gamal leaves as diuretic by measuring urine volume output and Na⁺, Cl⁻, dan K⁺ ion contents. Th…

UJI AKTIVITAS PENYEMBUHAN LUKA TERBUKA FRAKSI ETIL ASETAT DAUN SINGKONG (Mani…

National injury prevalence tends to increase every year. Wounds must be healed immediately because they are an important role in maintaining homeostasis and have the potential to become chronic infections if not treated. Cassava leaves (Manihot esculenta) contain the main substance rutin or quercetin 3-O-rutinoside (flavonoids) and contain saponins and tannins as anti-inflammatory, antibacteria…

UJI ANTINEFROLITHIASIS FRAKSI ETANOL DAUN KERSEN (Muntingia calabura L.) TERH…

Kidney stone disease (antinefrolithiasis) of calcium stone type is one of the health problems among Indonesian people. The use of diuretic drugs as a treatment for kidney stones can be replaced with natural ingredients to reduce the risk of side effects. Kersen leaves (Muntingia calabura L.) contain a lot of flavanes, flavones, flavanones, flavonols, and chalcones which are included in the flav…

UJI ANTINEFROLITHIASIS FRAKSI ETIL ASETAT DAUN KERSEN (Muntingia calabura L.)…

Kidney stone disease (antinefrolithiasis) of calcium stone type is one of the health problems among Indonesian people. The use of diuretic drugs as a treatment for kidney stones can be replaced with natural ingredients to reduce the risk of side effects. Kersen leaves (Muntingia calabura L.) contain a lot of flavanes, flavones, flavanones, flavonols, and chalcones which are included in the flav…

FORMULASI DAN UJI ANTIOKSIDAN ORALLY DISSOLVING FILM EKSTRAK ETANOL BUNGA KEC…

Kecombrang flower (Etlingera elatior) contains various secondary metabolite compounds, one of which is flavonoids that have antioxidant activity. Orally Dissolving Film (ODF) was formulated to cover the unpleasant taste of kecombrang flowers. Pullulan is used as a polymer due to its ease of solubility in water and has good film-forming properties. This study aims to determine the best formulati…

FORMULASI NANOPARTIKEL PERAK-MAGNETIT MENGGUNAKAN METODE GREEN SYNTHESIS DENG…

Thrombosis is a condition in which a blood clot (thrombus) forms in a blood vessel. Treatment involves antithrombotic agents such as anticoagulants, and researchers developed silver-magnetite nanoparticles (Ag-Fe₃O₄) using a green synthesis method using robusta coffee bean extract (Coffea canephora) containing chlorogenic acid as a natural reducing, stabilizing, and thrombolytic agent. The …

GREEN SYNTHESIS NANOPARTIKEL BESI OKSIDA EKSTRAK JARAH GAMBIR (UNCARIA GAMBIR…

Thrombosis is a leading global cause of cardiovascular diseases. While anticoagulants, antiplatelet agents, and thrombolytic therapies are the standard clinical treatments, iron oxide nanoparticles offer an alternative approach due to their ability to accumulate at sites of inflammation, such as thrombi and atherosclerotic plaques. These nanoparticles can act as photothermal agents, absorbing l…

KARAKTERISASI LIPOSOM PHOTOSENSITIZER PEMBAWA EKSTRAK KASAR NANAS (Ananas com…

Thrombosis is a condition that occurs due to an imbalance in the hemostasis system characterized by the formation of a blood clot (thrombus) in the blood vessel wall so that it can cause ischemic stroke disease. The anti-thrombotic drugs commonly used are thrombolytics. These drugs contain fibrinolytic enzymes such as protease enzymes. Pineapple (Ananas comosus (L.) Merr) is known to have an an…

OPTIMASI GREEN SYNTHESIS NANOPARTIKEL Ag-Fe3O4 MENGGUNAKAN EKSTRAK AIR BUNGA …

Thrombosis caused by blood clot formation can lead to serious complications. Conventional therapies carry a risk of bleeding, making photothermal therapy based on optical-magnetic nanoparticles such as AgNO₃ and Fe₃O₄ a safer alternative. These nanoparticles are synthesized via green synthesis using butterfly pea flower (Clitoria ternatea L.) extract, which contains flavonoids and anthocy…

FORMULASI DAN UJI ANTIOKSIDAN ORALLY DISSOLVING FILM EKSTRAK ETANOL BUNGA KEC…

Kecombrang flower (Etlingera elatior) are plant from the Zingiberaceae family which has potential as an antioxidant. Kecombrang flowers have a distinctive smell and sour taste. The orally dissolving film (ODF) formulation which uses a combination of HPMC polymer and maltodextrin was able to eliminate the unpleasant taste of kecombrang flowers. Orally dissolving film (ODF) preparations was made …

EFEK TERATOGENIK FRAKSI ETIL ASETAT DAUN MELINJO (Gnetum gnemon L.) PADA FETU…

One of the special toxicity tests is the teratogenic test which is carried out to obtain information on the presence of fetal abnormalities that occur due to the administration of test preparations during the formation of fetal organs (organogenesis period) and to complete safety data from the melinjo plant. The doses given were 69.48, 104.22, 138.96 and 173.7 mg/kgBW. The administration of the…

EFEK TERATOGENIK FRAKSI ETANOL DAUN KERSEN (Muntingia calabura L.) PADA FETUS…

Kersen leaves (Muntingia Calabura L) contain secondary metabolite compounds alkaloids, flavonoids and tanins. The use of herbal medicine during pregnancy needs to be considered because the drug can cross the placenta so that it can cause teratogenic effects on the fetus. Teratogenic toxicity research on the ethanol fraction of kersen leaves (Muntingia Calabura L) has been conducted to determine…

UJI AKTIVITAS ANTIDIABETES FRAKSI ETIL ASETAT KULIT BUAH PISANG KEPOK (MUSA B…

ABSTRAK Kulit pisang kepok, yang mengandung sejumlah senyawa metabolit sekunder seperti flavonoid, telah diketahui memiliki potensi sebagai agen antidiabetes. Penelitian ini bertujuan untuk mengevaluasi seberapa efektif fraksi etil asetat dari kulit pisang kepok dalam menurunkan kadar glukosa darah. Penelitian melibatkan pembagian tikus percobaan ke dalam enam kelompok: kelompok normal (mendapa…

EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN DEMAM TIFOID DENGAN METODE ATC/DDD…

Typhoid fever is an acute infectious disease of the small intestine caused by food and drinks contaminated with Salmonella typhi bacteria. The purpose of this study was to determine the profile of antibiotic drug use in typhoid fever patients, to determine the quantitative evaluation and qualitative evaluation of antibiotic use. This study is a descriptive study conducted retrospectively, the d…

ANALISIS HUBUNGAN KEPATUHAN PENGGUNAAN OBAT TERHADAP KUALITAS HIDUP PASIEN GA…

Hemodialysis is the primary treatment for patients with Chronic Kidney Failure (CKD). CKD Patients experience disruptions in fluid balance, electrolyte levels, acid-base balance, hormone production, and the secretion of toxic metabolic waste. This study aims to analyze the relationship between adherence to medication use and the quality of life of CKD patients with hemodialysis therapy at RSI S…

ANALISIS HUBUNGAN PENGGUNAAN OBAT PENURUN KADAR KOLESTEROL TERHADAP KUALITAS …

Pengobatan yang baik berpengaruh pada tingkat pengetahuan, kepatuhan minum obat penurun kadar kolesterol dan kualitas hidup pasien. Tujuan penelitian ini adalah menganalisis hubungan antara tingkat kepatuhan minum obat dengan kualitas hidup pasien hiperkolesterolemia di Rumah Sakit Islam Siti Khadijah Palembang. Desain penelitian dilakukan secara observasional analitik dengan pendekatan cross-s…

EFEK PREVENTIF FRAKSI ETIL ASETAT DAUN MELINJO (Gnetum gnemon L.) SEBAGAI HEP…

Melinjo leaves (Gnetum gnemon L.) is a plan that is often used as a medicinal ingredient because it has a high content of secondary metabolites. Secondary metabolites that are thought to act as hepatoprotectors are flavonoid. This study aims to determine the decrease in SGPT and SGOT levels of various doses, determine ED50 (Effective Dose 50) and determine the effect on the macroscopic and hist…

STANDARISASI DAN UJI TOKSISITAS AKUT EKSTRAK ETANOL RIMPANG TEMU MANGGA (Curc…

Temu mango rhizome (Curcuma amada Roxb.) is one of the plants that has anti-inflammatory and antidiabetic activities. The safety of using temu mango rhizome as a natural medicinal preparation must be supported by scientific research on toxicity testing. This study aims to evaluate the characteristics of acute toxicity of ethanol extract of temu mango rhizome to female Wistar rats using the Acut…

UJI HEPATOPROTEKTOR FRAKSI ETIL ASETAT DAUN MELINJO (Gnetum gnemon L.) DAN GA…

Melinjo leaves (Gnetum gnemon L.) have benefits in the field of traditional medicine. Melinjo leaves (Gnetum gnemon L.) contain secondary metabolite compounds such as flavonoids, saponins, tannins, phenolics, and saponins. This study aims to determine the hepatoprotector activity of ethyl acetate fraction of melinjo leaves (Gnetum gnemon L.) and hepatic histopathological picture of male white r…

Kimia Farmasi Analisis

Edition

-

ISBN/ISSN

978-623-180-167-8

Collation

vii, 118 hlm.; ilus., tab., 24 cm

Series Title

-

Call Number

615.1 Was k

ANALISA PERBANDINGAN RETURN DAN RISK SAHAM PERUSAHAAN INDUSTRI ROKOK DAN INDU…

Edition

-

ISBN/ISSN

-

Collation

xiv, 108 hlm.: Ilus., tab.; 28 cm

Series Title

-

Call Number

T591522005

DEFINED DAILY DOSE PENGGUNAAN OBAT ANTIHIPERTENSI DI PUSKESMAS MERDEKA PALEMBANG

Hipertensi adalah keadaan seseorang yang mengalami kenaikan tekanan darah diatas normal yaitu sistolik dan diastolik diatas 140/90 mmHg. Dalam proses terapinya, JNC8, AHA/ACC dan ESC menerbitkan pedoman terapi hipertensi dan merekomendasikan terapi lini pertama antara lain golongan ACEI, CCB, ARB dan obat diuretik golongan thiazid. Penelitian ini bertujuan untuk melihat penggunaan obat menurut …

FORMULASI DAN EVALUASI SEDIAAN ACNE PATCH TRANSDERMAL EKSTRAK ETANOL DAUN CAB…

Acne is a condition characterized by the accumulation of sebum from sebaceous glands in the skin layers, which often stimulates the growth of acne-causing bacteria, such as Staphylococcus aureus. Acne treatment can be performed using acne patches; however, commercial acne patches are only capable of absorbing sebum without providing antibacterial activity. This study aimed to enhance therapeuti…