STUDI IN SILICO EKSTRAK BUNGA KECOMBRANG (Etlingera Elatior) SEBAGAI ANTIBAKT…

Staphylococcus aureus infection is caused by a bacterium that colonizes various organs in the human body, particularly the upper respiratory tract, including the skin, nasal cavity, axilla, and inguinal area. The emergence of antibiotic-resistant S. aureus, known as MRSA and VRSA, presents a significant challenge in the treatment of such infections. Natural products, such as the torch ginger fl…

UJI HISTOKIMIA DAN STRUKTUR MIKROSKOPIS MEMAYE (Leea indica (Burm.f.) Merr.) …

Leea indica (Burm.f.) Merr. is traditionally used by the Besemah tribe to treat infectious and degenerative diseases such as hepatitis, liver disorders, and warts. This study aims to identify secondary metabolite groups with potential anti-infective and degenerative activity, as well as their distribution across the vegetative organs of L. indica using histochemical tests method and to characte…

PENGARUH EKSTRAK ETANOL RIMPANG TEMU MANGGA (CURCUMA MANGGA VAL) TERHADAP ANT…

This study aims to determine the effect of the use of ethanol extract of temu mango rhizome (Curcuma mangga Val) on anti-inflammatory in mice (Mus musculus) Swiss Webster Strain. The method used is an experimental method with a completely randomized design (RAL) design consisting of 5 treatments and 6 replicates. The treatment consisted of one negative control group (Aquades), one positive cont…

PENGARUH EKSTRAK AQUADES RIMPANG TEMU MANGGA (CURCUMA MANGGA VAL.) TERHADAP A…

This study aims to determine the effect of aqueous extract of Curcuma mangga Val. rhizome on the anti-inflammatory response in mice (Mus musculus). The study employs an experimental method with a completely randomized design (CRD) consisting of five treatment groups: a negative control (aqueous solution), a positive control (Sodium Diclofenac 0.13 mg/kgBW), and three doses of Curcuma mangga rhi…

UJI AKTIVITAS ANTIHIPERURISEMIA EKSTRAK ETANOL BUNGA BUGENVIL UNGU (Bougainvi…

flavonoid compounds and has the potential as an antihyperuricemia. This study aims to evaluate the antihyperuricemia activity of ethanol extract of B. spectabilis in male white rats of the Wistar strain. Extraction was carried out by the maceration method using 96% ethanol. The extract was characterized and tested the antihyperuricemia activity used 35 rats male were divided into 7 groups: norm…

UJI AKTIVITAS ANTIHIPERURISEMIA EKSTRAK ETANOL DAUN PACAR KAYU (Lawsonia iner…

Lawsonia inermis L. is one of the traditional medicinal plants that are effective as analgesics. The analgesic effect was related to the ability of the substance to reduced uric acid levels (antihyperuricemia). This study aims to determine the antihyperuricemia activity of ethanol extract of L. inermis leaves using male white rats of the Wistar strain induced in hyperuricemia condition. The stu…

UJI ANALGETIK DAN ANTI INFLAMASI EKSTRAK DAN FRAKSI DAUN SEBURO (Garcinia for…

The ethanol extract of seburo leaves (Garcinia forbesii King) contains flavonoid, alkaloid, phenolic, saponin and steroid compounds which are potentially active as an analgesic and anti-inflammatory. This study aims to determine the characteristics of the extract as well as the analgesic and anti-inflammatory effects of the ethanol extract and fractions with different solvent polarities from se…

UJI AKTIVITAS DIURETIK EKSTRAK ETANOL DAUN SUNGKAI (Peronema canescens jack.)…

The sungkai leaf (Peronema canescens jack.) is known to contain flavonoid compounds with potential diuretic properties. This study aimed to evaluate the diuretic activity of ethanolic extract from sungkai leaves through preclinical tests on experimental animals divided into six treatment groups. These groups consisted of a normal control (aquadest), a negative control (NaCMC), a positive contro…

UJI ANALGETIKA DAN ANTIINFLAMASI EKSTRAK DAN FRAKSI DAUN KARDIA (Bellucia pen…

The Kardia plant (Bellucia Pentamera Naudin), a member of the Melastomataceae family, contains compounds such as steroids, triterpenoids, and flavonoids, which exhibit potential analgesic and anti-inflammatory properties. This study aims to characterize the extract and evaluate its analgesic and anti-inflammatory effects based on the reduction in writhing behavior in mice and edema volume in ra…

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK BERGRADIEN EMPAT TANAMAN OBAT ANTIHIPERTENS…

Free radical that can cause damage to body cells by oxidative stress as a trigger factor for degenerative diseases with the presence of antioxidant compounds able to counteract free radical. Medical plants ciplukan, guajava, katuk, and cat’s whiskers are utilized as antihypertensive traditional medicine because their bioactive compounds support blood pressure control. This study was conducted…

OPTIMASI FORMULASI NANOPARTIKEL EKSTRAK ETANOL DAUN KELOR (Moringa oleifera L…

Moringa leaf (Moringa oleifera L.) are proven to contain secondary metabolites, one of which is flavonoids in the form of quercetin which has the ability as an anticancer. This study aims to determine the optimum formula of nanoparticles from a variety of alginate chitosan coatings at concentrations of 0.3% and 0.6% conjugated with folic acid. Moringa leaf extract was obtained through maceratio…

UJI AKTIVITAS PENYEMBUHAN LUKA BAKAR SUBMIKRO EMULSI EKSTRAK DAUN SAMBILOTO D…

Andrographis paniculata (Burm.f.) Nees) contains andrografolid, a compound that has anti-inflammatory, antibacterial, and antioxidant activities to accelerate burn wound healing. This study evaluated the preparation of submicro emulsion of bitter melon leaf extract with Tween 20 and PEG-400 at a concentration of 10% and tested the burn wound healing activity in Wistar rats. This study was divid…

OPTIMASI FORMULASI NANOPARTIKEL EKSTRAK DAUN KENIKIR (Cosmos caudatus Kunth.)…

Kenikir leaves (Cosmos caudatus Kunth.) contain flavonoid group compound quercetin which has potential as anti-cancer. The extract of kenikir leaves has low solubility and bioavailability so that a modification of the drug delivery system is needed in the form of folic acid-conjugated chitosan-alginate polymer-based nanoparticles. Folic acid-conjugated chitosan carries the drug to folate recept…

PREPARASI DAN UJI AKTIVITAS ANTI NEFROLITHIASIS NANOSUSPENSI FRAKSI DAUN MELI…

Gnetum gnemon leaves contained flavonoids that had the potential to dissolve kidney stones by increasing urinary citrate excretion and diuresis. The low bioavailability of fractions required nanoparticle dosage forms as an option to increase the effectiveness of the delivery system. This study aimed to determine the percentage of nanosuspension entrapment efficiency used for in vivo tests and t…

POTENSI ANTIINFLAMASI EKSTRAK ETANOL HERBAL SAMBILOTO (ANDROGHAPIS PANICULATA)

Inflammation is the body's protective mechanism against tissue damage caused by physical trauma, chemical irritation, or microbial infection. However, the use of synthetic anti-inflammatory drugs, such as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs), often leads to side effects, including gastrointestinal irritation and impaired kidney function. Sambiloto (Andrographis paniculata) is an herba…

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAN KOMBINASI EMPAT TUMBUHAN OBAT ANTIHIPER…

The human body that is exposed to excess free radicals in a prolonged period can cause oxidative stress and various diseases so antioxidant compounds are needed to counteract free radicals. This study was conducted with the aim of determining the strongest antioxidant activity of ciplukan leaves, guava leaves, katuk leaves and cat whisker leaves that have been used empirically by the people of …

UJI TOKSISITAS AKUT FRAKSI ETIL ASETAT DAUN GAMAL (Gliricidia sepium) TERHADA…

Gamal leaves (Gliricidia sepium) have pharmacological activity as anthelmitic, hepatoprotector and antibacterial. The content of secondary metabolites in the ethyl acetate fraction of gamal leaves are flavonoids, tannins and saponins. The purpose of this study was to determine the effects of acute toxicity of the ethyl acetate fraction of gamal leaves with testing parameters of biochemical leve…

PREPARASI DAN UJI AKTIVITAS ANTINEFROLITIASIS NANOSUSPENSI FRAKSI ETIL ASETAT…

Kidney stones (nephrolithiasis) were a common health problem in Indonesia. The kersen leaf (Muntingia calabura L.) contained flavonoid compounds that acted as diuretics. The use of nanosuspension preparations was chosen to enhance the effectiveness and bioavailability of the fraction in delivering the active substance to the target. The aim of this study was to determine the %EE and characteriz…

PREPARASI DAN UJI ANTINEFROLITIASIS FRAKSI ETANOL DAUN KERSEN (Muntingia cala…

Daun kersen (Muntingia calabura L.) diketahui memiliki efek farmakologi sebagai antinefrolitiasis karena mengandung senyawa flavonoid yang dapat berikatan dengan kalsium pada batu ginjal dan meningkatkan ekskresi urin. Senyawa bahan alam mempunyai kelarutan dan bioavailabilitas yang rendah dalam air sehingga dapat diatasi dengan inovasi sediaan berupa nanosuspensi. Penelitian ini bertujuan untu…

KRATOM: Kajian Botani, Fitokimia, Farmakologi, Isolasi, dan Analisis

Edition

-

ISBN/ISSN

978-623-02-2723-3

Collation

x, 101 hlm.; 20 cm

Series Title

-

Call Number

582.12 Fir k

STUDI IN SILICO POTENSI SENYAWA PADA DAUN SIRIH (Piper betle L.) SEBAGAI AGEN…

Hyperlipidemia is characterized by increased normal levels of plasma lipids such as cholesterol, triglycerides, cholesterol esters, phospholipids, and sometimes plasma lipoproteins, including very low-density lipoproteins (VLDL) and low-density lipoproteins (LDL), along with decreased high-density lipoproteins (HDL). This study used an in silico approach to predict the molecular potential of be…

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN ALPUKAT (PERSEA AMERICANA), DAUN JAMBU…

Long-term exposure to excess free radicals in the body can cause oxidative stress and various diseases, so antioxidant compounds are needed to neutralize free radicals. This research was conducted to determine the strongest antioxidant activity of avocado leaves, water guava leaves and cherry leaves which have been used empirically by the Ogan Ilir community. The extract with the strongest anti…

DOMESTIKASI BUAH MERAH

Edition

-

ISBN/ISSN

978-602-440-864-0

Collation

82 hlm. : ill. ; 23 cm.

Series Title

-

Call Number

634.6 Dar d

OPTIMASI FORMULA NANOSTRUCTURED LIPID CARRIER EKSTRAK KULIT JERUK MANIS (Citr…

The utilization of sweet orange peel is still minimal as it is often overlooked after fruit processing for consumption, despite being rich in bioactive compounds, including flavonoids, especially for topical preparations. Previous research has mainly focused on conventional formulations with limitations in skin penetration. The Nanostructured Lipid Carrier (NLC) delivery system can enhance perc…

AKTIVITAS ANTIOKSIDAN SENYAWA METABOLIT SEKUNDER DARI FRAKSI ETIL ASETAT DAUN…

Excessive free radicals in the body can cause oxidative stress conditions which result in tissue damage. This condition can be prevented by consuming antioxidants. Cherry leaves (Muntigia calabura L.) often used as a medicinal plant and are believed to have antioxidant properties. Based on previous research, methanol extract of cherry leaves has strong antioxidant activity, while the ethyl acet…

PEMISAHAN FRAKSI KOLOM DARI FRAKSI ETIL ASETAT DAUN KERSEN (MUNTINGIA CALABUR…

Kersen leaves (Muntingia calabura L.) have been proven to have antioxidant properties, both in the form of crude extracts and fractions. The ethyl acetate fraction of kersen leaves separated by vacuum liquid column chromatography has strong antioxidant activity (IC50 43,40 µg/mL). This research is a continuation of the previous research by further separating the fraction of vacuum liquid colum…

EVALUASI AKTIVITAS ANTIOKSIDAN DAN ANTIINFLAMASI FRAKSI DAUN SUKUN (Artocarpu…

Plants that contain high levels of flavonoid and phenol compounds have the potential to act as antioxidants and anti-inflammatories. One of them is the breadfruit plant (Artocarpus altilis). This study aims to determine the antioxidant and anti-inflammatory activity of breadfruit leaf fractions. The research began with extraction by maceration using solvents with varying polarities (n-hexane, e…

EFEKTIVITAS EKSTRAK BINAHONG (ANREDERA CORDIFOLIA) TERHADAP ZONA HAMBAT BAKTE…

Background: Staphylococcus aureus is a gram-positive bacterium that causes skin diseases, pneumonia, respiratory tract infections, nosocomial bacteremia and is resistant to antibiotics. The incidence of antibiotic-resistant Staphylococcus aureus is increasing. Binahong is a herbal plant that has many benefits, one of which is as an antibacterial. Methods: This study used an experimental design.…

EFEKTIVITAS PEMBERIAN LIDOKAIN 3,5 mg/KgBB 20ml INTRAPERITONEAL TERHADAP NYER…

Background: Post-cesarean section pain is a clinical challenge commonly encountered in medical practice. Despite various approaches to postoperative pain management, achieving optimal pain control remains challenging. One therapy being explored is intraperitoneal lidocaine administration. Lidocaine is known to have potential analgesic effects and may give the operator a benefit in reducing post…

PEMISAHAN SENYAWA METABOLIT DARI FRAKSI n-HEKSANA KAYU BATANG MURBEI PUTIH (M…

Separation of metabolite compounds from the n-hexane fraction of the wood of the M. alba L. plant has not been widely carried out. TLC analysis showed that M. alba L. has many metabolite compounds. This research was aimed to determine metabolite compounds from the n-hexane fraction of the wood of the M. alba L. plant using the gas chromatography-mass spectrometry (GC-MS) method. The extraction …