Background. Laryngopharyngeal reflux (LPR) is a pathological condition caused by the backflow of stomach contents into the larynx and pharynx, causing symptoms in the upper respiratory tract. One of the suspected risk factors is caffeine consumption, as it can decrease lower esophageal sphincter pressure and increase gastric acid secretion. Medical students tend to consume caffeinated beverages…
Background: Acute ischemic stroke is a major cause of global morbidity and mortality. Systemic inflammation plays a key role in its pathogenesis, and the neutrophil-to-lymphocyte ratio (NLR) is used as an inflammatory indicator. Elevated NLR is suspected to correlate with stroke severity assessed using the NIHSS. Methods: This retrospective observational analytic study used medical records of a…
Mosquitoes are vectors of infectious diseases such as dengue fever, malaria, and filariasis. Their breeding activity is strongly influenced by environmental factors, particularly the physical and chemical characteristics of water in potential breeding containers. This study aimed to analyze the correlation between water’s physical and chemical conditions and the number of mosquito larvae in B…
Kenikir leaves (Cosmos caudatus) contain various bioactive compounds and have a relatively high total protein content compared to other plant leaves. Ammonium sulfate precipitation is one of the common methods applied for protein isolation. However, there are currently no available data comparing the protein content and purity of kenikir leaves proteins precipitated with different concentration…
Background: Impetigo is a superficial skin infection in children mainly caused by Staphylococcus aureus. Although mupirocin is effective, long-term use may cause side effects and resistance. The pineapple core (Ananas comosus L. Merr.) contains bioactive compounds with potential antibacterial effects against S. aureus. This study aimed to evaluate the efficacy of pineapple core extract on the i…
Chronic Suppurative Otitis Media (CSOM) is a persistent middle ear infection characterized by tympanic membrane perforation and ear discharge, which may lead to hearing impairment and serious complications. This study aimed to determine the association between risk factors and comorbidities with the type of CSOM at the ENT-HN Department of Dr. Mohammad Hoesin General Hospital Palembang in 2025.…
Background: Pleural effusion is a common clinical manifestation encountered in internal medicine and pulmonology practice, with various etiologies, both transudative and exudative. In Indonesia, the most frequent causes of pleural effusion are tuberculosis, followed by malignancy and heart failure. Analysis of patient characteristics and pleural fluid is essential to determine the type of effus…
Background. Linezolid is an effective second-line drug for the treatment of drug-resistant tuberculosis (DR-TB), but it is often associated with hematological adverse effects. Patient characteristics such as age, residence, body mass index, serum albumin level, HIV status, diabetes mellitus, and treatment duration are suspected to contribute to these events. This study aimed to analyze the rela…
Background. Placenta previa is a condition in which the placenta implants in the lower uterine segment, close to or covering the internal cervical os, either partially or completely. Without early identification, placenta previa can cause antepartum hemorrhage, which can lead to maternal death. This study aims to identify the distribution of risk factors and classification of placenta previa in…
Background: Status epilepticus (SE) is one of the most common neurological emergencies requiring immediate management. This study aimed to identify the characteristics of precipitating factors of status epilepticus among pediatric patients at Dr. Mohammad Hoesin General Hospital Palembang. Method: This research used a retrospective descriptive design with a cross sectional approach. Data were c…
Background. Human Immunodefeciency Virus (HIV) is an RNA virus that targets the immune system, particularly CD4+ cells, rendering individuals more susceptible to opportunistic infections, including Hepatitis C Virus (HCV). HCV/HIV coinfection has become an increasingly complex public health issue, as both viruses share similar transmission routes, especially through the sharing or needles and h…
Background. Dengue infection is a viral disease that presents with a wide spectrum of clinical manifestations, ranging from mild febrile illness to severe hemorrhage and shock. During the critical phase, plasma leakage may occur characterized by increased hematocrit levels and decreased platelet counts. This study aimed to analyze the association between platelet count and hematocrit levels wit…
Background: Beta-thalassemia major is a hereditary blood disorder characterized by impaired hemoglobin production, requiring lifelong regular blood transfusions. Iron overload, measured by serum ferritin levels, and nutritional problems are major complications that affect patients’ quality of life. This study aimed to analyze the relationship between serum ferritin levels and nutritional stat…
Low birth weight (LBW) is one of the main causes of increased neonatal morbidity and mortality. Infants with a birth weight of less than 2,500 grams have an immature immune system, making them more susceptible to systemic infections such as neonatal sepsis. This study aimed to determine the relationship between LBW and the incidence of neonatal sepsis at Mohammad Hoesin Hospital Palembang in 20…
Background: Obesity is a global health problem that continues to rise each year and can lead to various complications, including cardiovascular disease. One manifestation of cardiovascular disease is cardiomegaly, which can be assessed using the cardiothoracic ratio index (CTR) on chest radiographs. This study was conducted to analyze the relationship between obesity degree and cardiothoracic r…
Background: Vector-borne diseases such as dengue fever continue to pose significant public health challenges in Palembang. The breeding of mosquito vectors is influenced not only by environmental conditions but also by the knowledge, attitudes, and practices of sanitation workers. This study aimed to describe potential water-holding containers serving as mosquito breeding sites, determine larva…
Hearing loss is one of the most common sensory disorders in children and can significantly affect language, cognitive, and social development. Brainstem Evoked Response Audiometry (BERA) plays an important role in assessing the function of the auditory nerve pathway, especially in infants and children who are difficult to evaluate through behavioral tests. This study was descriptive in nature, …
Problem-Based Learning (PBL) is an active learning method that places students at the center of the learning process. The utilization of AI in PBL can assist students in finding scientific references, formulating learning issues, and supporting self-directed learning. This study aims to determine the use of AI technology in the implementation of PBL among students of the Medical Education Progr…
Menopause leads to a decline in estrogen levels, which can cause various physiological and psychological disturbances. Although hormone therapy may be beneficial, it carries the risk of serious adverse effects, thereby necessitating safer alternative options. Luffa acutangula (gambas), a member of the Cucurbitaceae family, is known to contain secondary metabolites such as flavonoids and saponin…
Background: Medical students face a heavy academic workload, high performance expectations, and psychological pressure that may affect their mental health. Unmanaged academic stress can lead to future anxiety, particularly regarding career readiness and academic achievement. This study aimed to determine the relationship between academic stress levels and future anxiety among medical students a…
Childhood obesity is a major global public health problem with an increasing prevalence, including in Indonesia. This condition results from multifactorial interactions among genetic, behavioral, and environmental factors, such as high gadget use intensity and low levels of physical activity. This study aimed to analyze the relationship between gadget use intensity and physical activity with ob…
Background: Endometrial cancer is a gynecologic malignancy that originates from the endometrial lining. It ranks as the sixth most common cancer among women worldwide. The survival rate of patients with endometrial cancer is influenced by several factors, including age, stage, histopathological type, grade, and treatment modalities. This study aims to determine the survival rate of patients wit…
Background: Glaucoma can cause irreversible damage to the optic nerve, with aging is one of the major risk factors. However, data regarding the characteristics of glaucoma in elderly remain limited. Therefore, this study aims to identify the characteristics of glaucoma among adult patients receiving treatment at the Eye Polyclinic of Dr. Mohammad Hoesin General Hospital during the 2023–2024 p…
Background: Diabetic retinopathy (DR) is a common complication among patients with diabetes mellitus (DM), particularly those with type 2 DM, with a prevalence of up to 25.1%. This complication is one of the leading causes of vision loss in elderly diabetic patients, primarily due to hyperglycemia and alterations in metabolic pathways. This study aims to evaluate the prevalence and characterist…
Background: The development of medical science, which is closely related to life safety and health benefits, requires students to continuously update their knowledge and engage in lifelong learning. Game-based learning (GBL) presents itself as an innovative learning method that offers active interaction. Modified Monopoly has the potential to improve SDL readiness and is expected to support stu…
Background. Maternal Mortality Rate (MMR) remains a global health concern, with preeclampsia being one of the major contributing factors. Preeclampsia is a pregnancy complication characterized by hypertension and endothelial dysfunction that can lead to maternal and fetal death. In Palembang City, hypertension during pregnancy is the leading cause of maternal mortality, highlighting the importa…
Background: Lung tumors are abnormal growth and proliferation of cells within the lungs, which may be benign or malignant (cancer). Lung cancer remains the leading cause of cancer-related mortality worldwide and continues to show an increasing trend in incidence, including in Indonesia. Surgical interventions, both for diagnostic and therapeutic purposes can be performed through thoracotomy or …
Background. Vitamin D plays a vital role in calcium and phosphate metabolism, as well as immune and neuromuscular function. Deficiency remains a global health concern, including among healthcare professionals. Anesthesiology residents are particularly vulnerable due to prolonged indoor work and limited sunlight exposure. Vitamin D supplementation is one strategy to prevent deficiency. Therefore…
Background: Functional dyspepsia is a gastroduodenal complaint not caused by any organic disorder. The occurrence of functional dyspepsia is often associated with anxiety. Compared to older adults, anxiety is more commonly found in younger individuals, such as university students. This study aimed to determine the association between functional dyspepsia symptoms and anxiety among medical stude…
Thyroid heart disease is a cardiovascular disorder caused by thyroid hormone dysfunction, either hyperthyroidism or hypothyroidism, and can lead to cardiac rhythm abnormalities. Electrocardiography (ECG) is a non-invasive method that plays an important role in detecting electrical activity changes of the heart in this condition. This study aimed to describe the sociodemographic characteristics …