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UJI AKTIVITAS ANTIDEPRESAN EKSTRAK ETANOL DAUN SUKUN (Artocarpus altilis) TER…
Breadfruit leaves (Artocarpus altilis) contain flavonoids and quercetin which are thought to have potential as antidepressants. This study aims to determine the effect and know the best concentration of ethanol extract of breadfruit leaves as an antidepressant. Parameters observed include immobility time, number of line crossings, length of time mice fall, amount of sucrose consumption, and cha…
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- xviii, 57 hlm.; ilus.; tab.; 28cm
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- T1440182024
UJI TOKSISITAS SUBKRONIS EKSTRAK ETANOL DAUN JENGKOL (Archidendron jiringa) P…
Jengkol (Archidendron jiringa) is one of the medicinal plants that can be used as traditional medicine. The ethanol extract content of jengkol leaves is reported to have many pharmacological activities such as anti-inflammatory, anti-hyperuricemia, anti-hyperlipidemia and immunostimulant. However, the level of safety of using this plant is not yet known. This study aims to determine the nature …
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- xix, 102 hlm.; ilus.; tab.; 28cm
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- T1440032024
ANALISIS TINGKAT KEPATUHAN PENGGUNAAN OBAT TERHADAP KUALITAS HIDUP PASIEN PEN…
Coronary Heart Disease (CHD) is a condition plaque forms in the arteries of the heart which can cause a heart attack. This buildup of plaque in the coronary arteries is called atherosclerosis. This study aims to determine patient demographics and the relationship between the level of compliance and the quality of life of CHD patients at RS Islam Khadijah Palembang. The analytical observational …
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- xvii, 84 hlm.; ilus.; tab.; 28cm
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- T1440152024
ANALISIS PENGADAAN DAN PERENCANAAN OBAT DI PUSKESMAS KOTA PALEMBANG BERDASARK…
Puskesmas merupakan fasilitas kesehatan yang menjadi tujuan pertama pasien. Oleh karena itu, diperlukan ketersediaan perbekalan farmasi yang memadai. Pasien yang datang ke puskesmas kadang mengalami keluhan obat kosong. Hal ini dapat terjadi karena kurangnya kesesuaian perencanaan dan pengadaan obat yang dapat menyebabkan terapi pasien tidak maksimal. Penelitian ini bertujuan untuk menganalisis…
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- xvii, 36 hlm.; ilus.; 29 cm
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- T1458402024
KORELASI PERAN DUKUNGAN KELUARGA TERHADAP KEPATUHAN MINUM OBAT PASIEN SKIZOFR…
Skizofrenia merupakan gangguan jiwa yang mengganggu pemikiran dan persepsi. Terapi Skizofrenia memerlukan kepatuhan yang baik untuk mencapai keberhasilan terapi dan mengurangi resiko kekambuahan pasien. Prevalensi skizofrenia di Indonesia mencapai 6,7 per 1.000 rumah tangga dan jenis terbanyak diduduki oleh Skizofrenia Paranoid. Salah satu faktor yang dapat memengaruhi kepatuhan mi-num obat ada…
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- xix, 52 hlm.; ilus.; 29 cm
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- T1457702024
FORMULASI GEL TABIR SURYA EKSTRAK DAN FRAKSI DAUN NASI NASI (Syzygium zeylani…
Excessive sun exposure caused skin redness, inflammation, and even skin cancer. One effective way to protect the skin from the sun is by using sunscreen. Nasi-nasi leaves (Syzygium zeylanicum (L.) DC) had the potential to serve as a natural sunscreen due to their phenolic compounds, which could absorb harmful ultraviolet (UV) rays. This study aimed to explore the potential of sunscreen gel extr…
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- xvii, 111 hlm.; ilus.; tab.; 28cm
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- T1442242024
UJI ANTINEFROLITHIASIS FRAKSI ETANOL DAUN MELINJO (Gnetum gnemon L.) TERHADAP…
Melinjo leaves (Gnetum gnemon L) is one plant that has many properties, one of which is as a diuretic. Active compounds such as alkaloids, flavonoids, steroids, and tannins can be found in melinjo. Antinephrolithiasis testing of ethanol fraction of melinjo leaves was carried out in vivo with the aim of determining the effect on ureal levels, creatinine and calcium, crystalluria and urine pH, as…
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- xviii, 137 hlm.; ilus.; tab.; 29 cm.
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- T1453502024
UJI EFEK ANTIDIABETES FRAKSI N-HEKSAN KULIT BUAH PISANG (Musa balbisiana C.) …
Kulit buah pisang kepok (Musa balbisian C.) diketahui mengandung metabolit sekunder flavonoid yang memiliki efek antidiabetes. Tujuan dilakukan penelitan ini untuk mengetahui efektivitas penurunan kadar glukosa darah fraksi n-heksan kulit buah pisang . Penelitian ini dibagi menjadi 6 kelompok yaitu kelompok normal (suspense Na-CMC 0,5%), kontrol positif (metformin 9mg/kgBB), kontrol negatif (su…
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- vii, 90 hlm.; tab.; illus.; 29 cm
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- T1458792024
UJI KADAR FLAVONOID TOTAL DAN AKTIVITAS ANTIOKSDIAN SECARA IN VITRO PADA FRAK…
Free radical can trigger chain reactions that cause damage to cell-forming particles that can have an impact on health. One of the plants that has the potential as a source of antioxidants is purple sweet potato leaves (Ipomoea batatas L. Poir) which contains a secondary metalbolite component with antioxidant effectiveness relatively higher than tocopherol. This study aims to determine the Anti…
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- xiv, 41 hlm.; ilus.; tab.; 29 cm.
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- T1446462024
PREPARASI DAN UJI AKTIVITAS ANTIDIABETES NANOSUSPENSI EKSTRAK DAUN MELINJO (G…
Melinjo leaves has pharmacological activity as an antidiabetic because it contains flavonoid compounds which can inhibit glucose absorption, stimulate insulin secretion or act as insulin and can regulate the work of enzymes that play a role in carbohydrate metabolism. The effectiveness and bioavailability of extracts tend to be low so that the formula in the form of nanosuspension is an option …
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- xviii, 105 hlm.; ilus.; tab.; 29 cm.
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- T1451092024
PREPARASI DAN UJI AKTIVITAS ANTIDIABETES NANOSUSPENSI EKSTRAK DAUN MELINJO (G…
Melinjo leaves are known to have pharmacological activity as antidiabetics because they contain flavonoid compounds that can reduce blood glucose levels with their ability to act as antioxidants that protect β-cell damage as insulin producers and can increase insulin sensitivity. The effectiveness, bioavailability, and solubility of extracts tend to be low, so the formula in the form of nanosu…
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- xix, 101 hlm.; ilus.; tab.; 29 cm.
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- T1449962024
UJI AKTIVITAS ANTIDEPRESAN EKSTRAK ETANOL DAUN CEMPEDAK (Artocarpus champeden…
Cempedak (Artocarpus champeden) leaves contain flavonoids that are efficacious as antioxidants which are thought to have potential as antidepressant activity. This study aims to determine the effect of cempedak leaf ethanol extract as an antidepressant and find out the best concentration of cempedak leaf ethanol extract as an antidepressant. Parameters observed included length of fall, immobili…
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- xvii, 99 hlm.; ilus.; tab.; 28cm
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- T1440172024
UJI AKTIVITAS HAIR SERUM NANOPARTIKEL EKSTRAK DAUN TEH (CAMELLIA SINENSIS L.)…
Hair serum is one of the cosmetic preparations that has a high concentration of active ingredients so that its effectiveness can be felt faster. Tea leaves contain about 42% polyphenolic compounds in the form of catechins that can stimulate cell proliferation in hair dermal papilla cells by suppressing the production of Tumour Necrosis Factor alpha (TNF-alpha) that triggers baldness. This study…
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- xvii, 69 hlm.; ilus.; 29 cm
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- T1319032023
UJI AKTIVITAS EKSTRAK ETANOL DAUN SUNGKAI (Peronema canescens Jack.) TERHADAP…
Penelitian ini dilakukan untuk mengetahui aktivitas dari ekstrak daun sungkai (Peronema canescens Jack.) yang memiliki senyawa flavonoid terhadap pertumbuhan dari probiotik Lactobacillus plantarum. Campuran dari ekstrak daun sungkai dan probiotik L. plantarum yang memiliki metabolit sekunder masing-masing diharapkan dapat menghambat bakteri Escherichia coli dengan lebih baik. Uji antibakteri di…
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- xix, 136 hlm.; ilus.; 29 cm
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- T952402023
OPTIMASI ORALLY DISSOLVING FILM (ODF) ASAM USNAT DENGAN POLIMER PVP K-30 MENG…
Asam usnat adalah komponen kimia umum yang ditemukan dalam sel lumut dan merupakan komponen kimia dari temuan utama metabolit pada semua spesies Usnea sp. Penggunaan asam usnat sebagai obat masih terbatas karena kelarutannya yang kurang baik dalam air dan termasuk kedalam BCS kelas II. PVP digunakan sebagai pelarut dalam sediaan oral dan sediaan parenteral, dan telah terbukti telah meningkatkan…
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- xv, 63 hlm.; ilus.; 29 cm
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- T1296742023
UJI AKTIVITAS HEPATOPROTEKTOR EKSTRAK ETANOL DAUN GAMAL (GLIRICIDIA SEPIUM) P…
Gamal leaves (Gliricidia sepium) contain several secondary metabolites, considered efficacious as hepatoprotector. This study aims to determine the activity of the ethanol extract of Gamal leaves as a hepatoprotector by measuring levels of SGPT, SGOT and ALP and liver histopathology of Wistar male white rats. Mice were divided into six groups: normal group (0.5% Na CMC suspension), positive gro…
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- xvi, 49 hlm.; ilus.; 29 cm
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- T947432023
UJI AKTIVITAS ANTIOKSIDAN FIKOSIANIN DARI MIKROALGA SPIRULINA PLATENSIS SECAR…
One source of antioxidants is phycocyanin from the microalga Spirulina platensis which has pharmacological activity as a natural antioxidant. This study aims to determine the antioxidant activity of phycocyanin from Spirulina platensis microalgae in vitro using the DPPH and FRAP methods. Based on the results of this study, the antioxidant activity of the positive control of vitamin C have IC50 …
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- xx, 30 hlm.; ilus.; 29 cm
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- T1054072023
OPTIMASI SEDIAAN SUNSCREEN SPRAY GEL EKSTRAK ETANOL DAUN ALPUKAT (Persea amer…
KIN THAT IS EXPOSED TO EXCESSIVE SUN EXPOSURE CAN RESULT IN SEVERAL LOSSES THAT CAN DAMAGE THE SKIN INCLUDING PREMATURE AGING, SKIN DAMAGE BY ULTRAVIOLET RADIATION, AND SUNBURN OR BURNING REACTIONS. SUNSCREEN IS NEEDED TO PROTECT THE SKIN FROM DAMAGE CAUSED BY UV RAYS. ZINC OXIDE IS A PHYSICAL SUNSCREEN AGENT THAT IS OFTEN USED AS AN ACTIVE INGREDIENT IN SUNSCREEN PREPARATIONS. AVOCADO LEAVES H…
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- xvii, 122 hlm.; ilus.; 29 cm
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- T951332023
FORMULASI DAN UJI AKTIVITAS ANTIERITEMA GEL TABIR SURYA EKSTRAK ETIL ASETAT D…
Breadfruit leaves (Artocarpus altilis (Park.) Fosberg) are reported to contain flavonoids which have activity as photoprotective agents due to their ability to absorb UV light. This study aims to determine the effect of various extracts on the effect of the anti-erythema activity test of sunscreen gel with HPMC carrier. Sunscreen gels were made with ethyl acetate extract of breadfruit leaves us…
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- xv, 63 hlm.; ilus.; 29 cm
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- T1316742023
OPTIMASI GELLING AGENT PADA SEDIAAN GEL EKSTRAK SAMBILOTO (ANDROGRAPHIS PANIC…
Daun sambiloto (Andrographis paniculata (Burm.f.) Nees) merupakan tanaman yang mengandung senyawa aktif seperti andrografolida (diterpenlactone), flavonoid, asam quinic, steroid, saponin, alkaloid dan tanin yang memiliki potensi sebagai antiinflamasi, antioksidan, antibakteri, dan mempercepat penyembuhan luka. Penelitian ini bertujuan untuk mengoptimasi Gelling Agent pada sediaan gel ekstrak sa…
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- viii, 124 hlm.; ilus.; 29 cm
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- T944322023
FORMULASI DAN EVALUASI SPRAY GEL CHITOOLIGOSACCHRIDE SEBAGAI ANTI JERAWAT TER…
Chitooligosacchride is a complex compound of the glycoprotein group which has a 1,4 glucosamine bond. Chitooligosaccharide as a natural cationic antibacterial agent is widely believed to occur because it interacts and disrupts the structure of the cell wall or cell membrane. This study aims to determine the effect of variations of chitooligosacchride as an anti-acne against Propionibacterium ac…
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- xix, 67 hlm.; ilus.; 29 cm
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- T949432023
OPTIMASI ORALLY DISSOLVING FILM (ODF) ASAM USNAT DENGAN POLIMER PULLULAN MENG…
Asam usnat dapat ditemukan pada lumut, dan terutama melimpah seperti pada genus Alectia, Cladonia, Usnea, Lecanora, Ramalina dan Evernia. Banyak lumut dan ekstrak yang mengandung asam usnat telah digunakan untuk kosmetik dan pengobatan. Asam usnat masih terbilang jarang digunakan dalam pengobatan dikarenakan termasuk dalam BCS kelas II dan tergolong praktis tidak larut dalam air. Pembuatan Oral…
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- xvi, 63 hlm.; ilus.; 29 cm
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- T1296792023
ANALISIS PERENCANAAN OBAT DI 4 PUSKESMAS DI KOTA PALEMBANG TAHUN 2022
ABSTRACT Drug planning determines the type and amount of drugs aimed at implementing rational drug use and increasing the efficiency of drug use. However, patients often complain about the availability of drugs at the Health Center because of vacancies. This is due to the inaccuracy of drug planning and procurement. This study aimed to analyze drug procurement at the Palembang City Health Cente…
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- xviii, 137 hlm.; ilus.; 29 cm
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- T1045322023
PENGARUH EKSTRAK ETIL ASETAT DAUN SUKUN (Artocarpus altilis) TERHADAP PERBAIK…
Daun sukun (artocarpus altilis) dilaporkan memiliki kandungan flavonoid yang memiliki aktivitas antioksidan dan antiinflamasi yang berpotensi memperbaiki fungsi ginjal. Penelitian ini bertujuan untuk mengetahui pengaruh variasi dosis terhadap efek nefroprotektif. Parameter yang diamati meliputi volume urin, pH urin, kreatinin serum, ureum serum, protein urin, klirens kreatinin, serta dilakukan …
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- xviii, 137 hlm.; ilus.; 29 cm
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- T1044922023
FORMULASI DAN UJI AKTIVITAS ANTIDIABETES NANOSUSPENSI EKSTRAK DAUN KENIKIR (C…
Kenikir leaves has pharmacological activity as an antidiabetic because it contains flavonoid compounds in the form of quersetin which can become the α-glukosidase enzyme inhibitor so that excess blood glucose level can be lowered. The effectiveness and bioavailability of extracts tend to be low so that the formula in the form of nanosuspension is an option for improving the delivery system whi…
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- xviii, 86 hlm.; ilus.; 29 cm
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- T1057122023
EVALUASI MIKROANATOMI GINJAL PEMBERIAN SELF NANO EMULSION (SNE) EKSTRAK TEH P…
White tea has pharmacological activity as an antidiabetic because it contains polyphenol compounds in the form of epigallocatechin gallate (EGCG) which can inhibit the α-glucosidase enzyme so that blood glucose levels can be returned within normal limits. However, plant extracts have low oral bioavailability, so the formula in the form of SNEDDS (Self-Nano Emulsifying Drug Delivery Systems) is…
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- x, 97 hlm.; ilus.; 29 cm
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- T930412023
UJI AKTIVITAS ANTIOKSIDAN KOMBINASI EKSTRAK ETANOL DAUN SIRSAK (Annona murica…
Soursop leaf and sapodilla leaf contain secondary metabolit is flavonoid which is antioxidant. The study aimed to the characteristic of the ethanol extract soursop leaf (Annona muricata L.) and sapodilla leaf (Manilkara zapota L.), total flavonoid contents, and antioxidant activity of combine ethanol extract soursoup leaf and sapodilla leaf using DPPH method. The treatment of antioxidant activi…
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- xix, 71 hlm.; ilus.; 29 cm
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- T1056172023
UJI AKTIVITAS ANTIOKSIDAN FRAKSI ETIL ASETAT DAUN BELUNTAS (Pluchea indica L.…
Daun beluntas (Pluchea indica L.) mengandung metabolit sekunder seperti flavonoid yang berpotensi sebagai antioksidan. Tujuan penelitian ini adalah untuk mengetahui karakterisasi, jumlah kadar flavonoid total, dan pengaruh pemberian fraksi etil asetat daun beluntas terhadap kadar MDA, aktivitas enzim katalase, gambaran makroskopik dan histopatologi hepar tikus yang diinduksi CCl4, serta mengeta…
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- xviii, 73 hlm.; ilus.; 29 cm
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- T954322023
FORMULASI DISPERSI PADAT AZITROMISIN DENGAN POLYETILEN GLIKOL (PEG) 6000 DAN …
Azitromisin mempunyai sifat sebagai antibiotik turunan makrolida, namun memiliki kelarutan yang rendah dalam air. Sehingga dikelompokkan kedalam sistem klasifikasi biofarmasetika (BCS) kelas II. Berbagai cara telah dilakukan untuk meningkatkan laju disolusi, salah satunya dengan dispersi padat. Dispersi padat adalah campuran yang terdiri dari satu atau lebih zat aktif dalam pembawa yang bersifa…
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- xix, 76 hlm.; ilus.; 29 cm
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- T1050382023
ANALISIS HUBUNGAN PENGGUNAAN OBAT ANTIPSIKOTIK TERHADAP KEJADIAN EFEK SAMPING…
Skizofrenia merupakan salah satu ganggu jiwa berat yang ditandai dengan kesulitan pada penderita untuk membedakan antara nyata dan tidak nyata dalam kehidupan sehari-hari seperti halusinasi dan delusi. Manajemen terapi yang digunakan pada pasien skizofrenia adalah menggunakan terapi antipsikotik. Efek samping yang sering muncul akibat terapi antipsikotik adalah gejala ekstrapiramidal. Penelitia…
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- xv, 150 hlm.; ilus.; 29 cm
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- T942542023
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