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UJI TOKSISITAS AKUT FRAKSI ETIL ASETAT DAUN MELINJO (GNETUM GNEMON L.) TERHAD…
Fraksi etil asetat daun melinjo memiliki efek terapi sebagai antihiperlipidemia dan antidiare. Skrining fitokimia fraksi etil asetat daun melinjo mengandung senyawa tanin, fenolik, dan flavonoid. Senyawa yang terkandung pada fraksi etil asetat daun melinjo belum tentu aman, sehingga perlu diuji keamanannya dengan pengujian toksisitas. Penelitian ini telah dilakukan uji toksisitas akut fraksi et…
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- xx, 96 hlm.; Ilus.; 29 cm
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- T1057242023
UJI TOKSISITAS SUBKRONIS FRAKSI ETIL ASETAT DAUN UBI JALAR UNGU (Ipomoea bata…
Purple sweet potato leaves (Ipomoea batatas L.) is a traditional medicine so it is necessary to carry out safety tests, one of which is the subchronic toxicity test. This study aims to determine the effect subchronic toxicity of the ethyl acetate fraction of purple sweet potato leaves on male white rats of the Wistar strain. In this study, they were divided into 4 groups including the control g…
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- xix, 92 hlm.; Ilus.; 29 cm
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- T1263452023
UJI TOKSISITAS AKUT EKSTRAK ETANOL DAUN JENGKOL (Archidendron jiringa) TERHAD…
Daun jengkol (Archidendron jiringa) merupakan salah satu tanaman yang memiliki aktivitas antiinflamasi dan antihiperurisemia. Hasil skrining fitokimia menunjukkan ekstrak etanol daun jengkol mengandung senyawa saponin, tanin, flavonoid, dan steroid. Keamanan penggunaan daun jengkol sebagai bahan sediaan obat alami harus didukung oleh penelitian ilmiah mengenai pengujian toksisitas. Pada penelit…
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- xvi, 102 hlm.; Ilus.; 29 cm
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- T1045102023
UJI TOKSISITAS AKUT FRAKSI ETIL ASETAT DAUN UBI JALAR UNGU (Ipomoea batatas L…
Purple sweet potato leaves has activities as a medicine for boils, antipyretic, burns, hepatoprotectors, antioxidants and it is known that the ethyl acetate fraction of purple sweet potato leaves has antihyperlipidemic activity. The use of purple sweet potato leaves as a natural medicine must be supported by toxicity studies to ensure the safety of its use. The purpose of this study was to dete…
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- xviii, 106 hlm.; Ilus.; 29 cm
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- T1209492023
PENGARUH PENGOLAHAN FERMENTASI DAN PANAS TEPUNG BENGKUANG (Pachyrhizus erosus…
Jicama flour (Pachyrhizus erosus) contains an oligosaccharide compound in the form of inulin which acts as a natural prebiotic with low levels, so it needs to be modified to improve its prebiotic properties. This study aims to modify yam flour into resistant starch (RS3). Analysis was carried out on jicama flour without modification and modification by fermentation and autoclaving-cooling 3 cyc…
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- xix, 119 hlm.; Ilus.; 29 cm
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- T1178172023
IDENTIFIKASI TUMBUHAN PAKAN ALAMI GAJAH SUMATERA (ELEPHAS MAXIMUS SUMATRANUS)…
Sumatran elephants is one of large mammal distributed along the island of Sumatra. The population of Sumatran elephants (Elephas maximus sumatranus) may decline if there are no activities that refer to conservation, especially in wild populations. The main problem of elephant conservation is interaction with humans which causes habitat loss and degradation that affects elephant feeding activiti…
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- xv, 59 hlm.; Ilus.; 29 cm
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- T1121662023
UJI EFEK TERATOGENIK FRAKSI ETANOL DAUN UBI JALAR UNGU (Ipomoea batatas L) PA…
Purple sweet potato leaves (Ipomoea batatas L.) have been tested for acute toxicity at a dose of >2000 mg/KgBB which is classified as practically non-toxic, so further testing is required for teratogenic tests. The purpose of this study was to determine the level of safety of purple sweet potato leaves for the fetus when consumed by pregnant women. In this study, 4 treatment groups were used, n…
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- xvii, 101 hlm.; Ilus.; 29 cm
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- T1266202023
UJI EFEK ANTIDIABETES FRAKSI ETANOL BUNGA TELANG (Clitoria ternatea L.) PADA …
Butterfly pea flowers (Clitoria ternatea L.) contains secondary metabolites of anthocyanins and flavonoids which have antidiabetic activity. The purpose of this study was to determine the effectiveness of lowering blood glucose levels of the ethanol fraction of butterfly pea flowers. The experimental divided into 6 groups namely normal and negative control groups with 0.5% NaCMC, positive contr…
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- xviii, 96 hlm.; Ilus.; 29 cm
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- T1142152023
UJI EFEK ANTIDIABETES FRAKSI ETIL ASETAT DAUN KENCANA UNGU (Ruellia tuberosa …
Kencana Ungu (Ruellia tuberosa L.) leaves are known to contain secondary metabolites of flavonoids which have antidiabetic activity. The purpose of this research was to determine the effectiveness of reducing blood glucose levels of the ethyl acetate fraction of kencana ungu leaves. This study was divided into 6 groups, namely the normal group (0.5% Na-CMC suspension), positive control (1 IU/kg…
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- xix, 85 hlm.; Ilus.; 29 cm
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- T1142162023
UJI TOKSISITAS AKUT FRAKSI ETANOL DAUN KERSEN (Mutingia calabura L.) TERHADAP…
Kersen (Mutingia calabura L.) leaves have pharmacological effect as antioxidant, antibacterial, anti-inflammatory, antihyperuricemia, antiobesity, antidiarhheal, antihyperlipidemic, analgesic, anthelmintic. Kersen leaves contain secondary metabolites, alkaloid, flavonoid, tannin, saponin, steroids. High flavonoid compounds require toxicity testing. This study aimed to determine the acute toxici…
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- xx, 101 hlm.; Ilus.; 29 cm
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- T1050922023
UJI AKTIVITAS ANTIOSIDAN MIKROALGA SPIRULINA PLATENSIS DENGAN METODE DPPH DAN…
Spirulina platensis contains flavonoids and carotenoids which have pharmacological activity as antioxidants. This study aims to determine the content of phenolic and carotenoid compounds and antioxidant activity contained in Spirulina platensis microalgae using the DPPH (1,1-diphenyl-2-pikrihidrazyl) and FRAP (Ferric-Reducing Antioxidant Power) methods. The content of phenolic compounds obtaine…
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- xviii, 89 hlm.; Ilus.; 29 cm
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- T1056392023
PREPARASI DAN UJI AKTIVITAS ANTIDIABETES SEDIAAN NANOSUSPENSI EKSTRAK DAUN KE…
Daun ketepeng cina diketahui memiliki efek farmakologi sebagai antidiabetes alami dikarenakan mengandung senyawa flavonoid berupa kuarsetin yang mampu menghambat enzim α-glukosidase untuk menurunkan kadar glukosa dalam darah. Efektivitas dan bioavailibilitas ekstrak yang cenderung rendah sehingga dibuat sediaan dengan sistem penghantaran nanopartikel. Penelitian ini bertujuan untuk memformulas…
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- xvii, 121 hlm.; Ilus.; 29 cm
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- T1055772023
FORMULASI DAN ANALISIS MIKROBIOLOGIS LIPSTIK CAIR DENGAN PENGAWET ALAMI CHITO…
Liquid lipstick is a cosmetic type of lip color that is currently in great demand by consumers. Repeated use of liquid lipstick can cause the growth of pathogenic microbes such as Staphylococcus aureus and Candida albicans. Chitooligosaccharide is a derivative of chitosan resulting from the deacetylation of chitin and has been widely reported to have biological activity as an antimicrobial. Thi…
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- xix, 119 hlm.; Ilus.; 29 cm
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- T950142023
UJI AKTIVITAS GASTROPROTEKTIF EKSTRAK ETANOL RIMPANG TEMU IRENG (Curcuma aeru…
Ethanol extract of temu ireng rhizome (Curcuma aeruginosa Roxb.) contains many efficacious secondary metabolites, one of which is flavonoid, phenolic, and curcuminoid. The compound is thought to have the potential to be gastroprotective. This research aimed to determine the effect of differences in the dose of ethanol extract of temu ireng rhizome as gastroprotective on the evaluation parameter…
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- xvii, 106 hlm.; Ilus.; 29 cm
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- T1047642023
AKTIVITAS PREBIOTIK TEPUNG PISANG KEPOK (MUSA PARADISIACA FORMATYPICA) TERHAD…
Kepok banana (Musa paradisiaca formatypica) contains inulin and fructooligosaccharide (FOS) which act as natural prebiotics. This research was conducted to analyze the effect of kepok banana flour before and after modification with high pressure heating on the growth of L. plantarum using Design Expert 12®. Test standardization of the quality of banana flour kepok based on SNI 01-3751-2009. Mo…
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- xvii, 108 hlm.; Ilus.; 29 cm
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- T920912023
FORMULASI DISPERSI PADAT AZITROMISIN DENGAN KITOSAN DAN NATRIUM ALGINAT MENGG…
Azithromycin is a macrolide-derived antibiotic compound that is poorly water soluble. Various technologies are reported to overcome the solubility problem of poorly soluble drugs, one of which is solid dispersion technology. Solid dispersion refers to a group of solid products consisting of at least two different components, generally a hydrophilic matrix and a hydrophobic drug. Solid dispersio…
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- xix, 74 hlm.; Ilus.; 29 cm
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- T1220722023
UJI KADAR FENOLIK TOTAL DAN AKTIVITAS ANTIOKSIDAN SECARA IN-VITRO PADA TANAMA…
Research has been carried out on the anti-oxidant potence of kecombrang (Etlingera elatior), which includes the determination of total phenolic content and antioxidant activity of the extract, and the fractions of the kecombrang (E.elatior) plant. Determination of total phenolic content with gallic acid standard using Follin Ciocalteu reagent. The principle of this test is the formation of a bl…
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- xvii, 115 hlm.; ilus.; 29 cm
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- T891462023
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAN FRAKSI DAUN PUCUK IDAT (Cratoxyl…
Daun pucuk idat mengandung metabolit sekunder yaitu flavonoid, saponin, tanin, triterpenoid, steroid, dan fenolik yang memiliki aktivitas farmakologi sebagai antioksidan. Penelitian ini bertujuan untuk mengetahui karakteristik ekstrak etanol, pengaruh pemberian ekstrak etanol dan fraksi daun pucuk idat terhadap aktivitas antioksidan dengan mengukur kadar MDA, penentuan aktivitas enzim katalase,…
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- xxi, 142 hlm.; ilus.; 29 cm
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- T887122023
PROFIL STRES OKSIDATIF DAN MIKROANATOMI OTAK PEMBERIAN SELF-NANOEMULSIFYING D…
Stres oksidatif dapat menimbulkan kerusakan DNA sehingga dapat menurunkan fungsi kognitif. Katekin pada teh putih memiliki efek farmakologis sebagai antioksidan dapat dijadikan terapi peningkatan fungsi kognitif. Penelitian bertujuan untuk mengetahui nilai profil stres SOD, CAT, dan MDA serta mengetahui gambaran histopatologi hippokampus dan sel neuron. Penelitian menggunakan rancangan post tes…
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- xv, 93 hlm.; ilus.; 29
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- T890102023
PENGARUH PEMBERIAN FRAKSI N-HEKSAN DAUN UBI JALAR UNGU TERHADAP ALIRAN DAN PA…
Daun ubi jalar ungu (Ipomoea Batatas (L.) Lam.) mengandung senyawa beta-karoten yang memiliki efek farmakologis sebagai antiaterosklerosis. Penelitian ini bertujuan untuk melihat aktivitas fraksi n-heksan daun ubi jalar ungu dalam mengembalikan aliran dan faktor koagulasi darah tikus serta pengaruhnya terhadap gambaran histopatologi aorta tikus yang diinduksi suplemen tinggi lemak. Pada penelit…
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- ix, 95 hlm.; ilus.; 29 cm
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- T890962023
UJI AKTIVITAS ANTIOKSIDAN SEDIAAN NANOEMULSI MINYAK BIJI RAMI (Linum usitatis…
Flaxseed oil (Linum usitatissimum) has been shown to enhance the function of the antioxidant system due to its antioxidant compounds such as phenols and vitamin E. The development of flaxseed oil into stable dosage forms such as nanoemulsions is very potential from the point of view of the efficacies contained. This research was conducted to determine the concentration of flaxseed oil in nanoem…
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- xviii, 94 hlm.; ilus.; 29 cm
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- T893412023
UJI AKTIVITAS ANTIOKSIDAN SEDIAAN NANOEMULSI MINYAK SACHA INCHI (Plukenetia v…
Minyak Sacha Inchi (Plukenetia Volubilis L.) mengandung senyawa bioaktif yang bersifat antioksidan diantaranya yaitu flavonoid dan beberapa asam lemak tinggi yakni asam palmitat, asam stearat, asam oleat, asam linoleat, dan asam linolenat. Penelitian ini bertujuan untuk menentukan konsentrasi minyak sacha inchi dalam sediaan nanoemulsi yang memiliki aktivitas antioksidan terbaik kemudian dianal…
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- xvii, 84 hlm.; ilus.; 29 cm
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- T893252023
PENGARUH PEMBERIAN FRAKSI ETIL ASETAT DAUN UBI JALAR UNGU TERHADAP ALIRAN DAN…
Purple sweet potato leaves are plants that contain secondary metabolites of flavonoids, tannins and phenolics which are proven to have activity as a vasodilator and are able to increase the formation of Nitric Oxide (NO) as so as reducing atherosclerosis. The purpose of this study was to determine the effect of giving the ethyl acetate fraction of purple sweet potato leaves on blood flow and bl…
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- iv, 60 hlm.; ilus.; 29 cm
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- T890662023
PENGARUH PEMBERIAN ORALLY DISSOLVING FILM EKSTRAK BUAH MENGKUDU (Morinda citr…
Noni fruit (Morinda citrifolia L.) contains flavonoids that have immunomodulatory activity. Orally Dissolving Film (ODF) formulation removes the bitter taste and low bioavailability of extract. This study aims to determine the characteristics of ODF noni fruit extract and the immunomodulatory effects of ODF noni fruit extract in Wistar male rats induced by E. coli on the number of leukocytes, l…
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- xviii, 135 hlm.; ilus.; 29 cm
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- T1141362023
FORMULASI EKSTRAK DAUN GAMBIR (UNCARIA GAMBIR ROXB.) SEBAGAI KOSMETIK PEMBERS…
Catechins are flavonoid compounds that contain antioxidants that can prevent cell damage from free radicals and reduce excess melanin production by inhibiting the tyrosinase enzyme. Delivery of active substances is more effective when done in dosage forms, so gambir extract is formulated into facial cleansers that can deliver active substances properly. This study aims to obtain an optimum form…
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- xix, 101 hlm.; ilus.; 29 cm
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- T1050322023
PENGARUH PEMBERIAN ORALLY DISSOLVING FILM EKSTRAK DAUN KENIKIR (Cosmos caudat…
Kenikir leaves (Cosmos caudatus. Kunth) contain various secondary metabolic compounds, quercetin which has the potential as an immunomodulator. This study aims to determine number of leukocytes, lymphocytes, neutrophils, monocytes, CD4 T cells, ODF ethanol extract film of kenikir leaves in Wistar rat strain and macroscopic and histopathalogic images of spleen organs. The research used Spektrofo…
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- xviii, 146 hlm.; ilus.; 29 cm
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- T1140462023
OPTIMASI KONSENTRASI TWEEN 80 DAN PEG-400 DALAM SEDIAAN NANOEMULSI DAUN SAMBI…
Sambiloto leaves (Andrographis paniculata (Burm. f.) Wall. Ex Ness) has the potential as a photoprotective agent with a high content of quercetin and andrographolide. The preparation of Sambiloto leaves nanoemulsion was carried out to increase its photoprotective activity and stability. This study aims to determine the optimum concentration of Tween 80 and PEG-400 in the Sambiloto leaves nanoem…
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- xviii, 82 hlm.; ilus.; 29 cm
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- T944682023
EFEK PEMBERIAN SNACK BAR EKSTRAK DAUN PEGAGAN (Centella asiatica L.) KOMBINAS…
Cognitive function improvement is an ability to organize information for the better. One of the methods to improve it is functional food. Gotu kola leaves (Centella asiatica L.) and purple sweet potato (Ipomoea batatas L.) have high antioxidant contents of flavanoid, asiaticoside, triterpenoid, and anthocyanin compounds which are able to counteract free radicals. This research aims at determini…
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- xx, 91 hlm.; ilus.; 29 cm
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- T888232023
AKTIVITAS ANTIINFLAMASI TRANSDERMAL PATCH EKSTRAK DAUN MELINJO (Gnetum gnemon…
Inflammation can cause an uncomfortable response due to pain. Plants that can be used as anti-inflammatory come from melinjo leaf at dose of 563 mg/kg BB. Delivering the active substance is carried out as a transdermal patch. The use of plasticizers can improve the mechanical properties of patch preparations. This study aims to obtain the best formula for transdermal patch preparations for anti…
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- xvii, 102 hlm.; ilus.; 29 cm
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- T949402023
EFEK PEMBERIAN SELF-NANO EMULSION EKSTRAK WHITE TEA TERHADAP PROFIL INSULIN, …
White tea contains catechins which have pharmacological effects as antioxidants. This study used test animals in the form of male Wistar rats which were divided into seven groups: normal group, negative control (STZ-NA induced), positive control (STZ-NA and Glibenclamide induced), group 1 (STZ-NA induced and SNE base). , Group 2 (induced STZ-NA and SNE-white tea extract), group 3 (induced STZ-N…
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- xvii, 125 hlm.; ilus.; 29 cm
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- T889302023
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