Background: Porphyromonas gingivalis was one of the Gram-negative anaerobic bacteria that played an important role in the pathogenesis of periodontal disease. The increasing resistance of bacteria to synthetic antibiotics encouraged the search for alternative antibacterial agents from natural sources. Snakehead fish (Channa striata) was known to contain bioactive compounds such as albumin and m…
Introduction: S. aureus is one of the most frequently found and detected microorganisms in odontogenic infections of oral and cerebral abscesses. The treatment of odontogenic infections can be treated using antibiotics, which can be replaced by honey. Tembesu bitter black honey is a natural material that can be used as an antibacterial because it has high osmolarity, low pH (3,2-4,5), low water…
Diarrhoea is an infectious disease of the human digestive system tract, one of the bacteria that can cause diarrhoeal infections is Bacillus subtilis and Bacillus cereus, natural ingredients soursop seeds (Annona muricata L.) are known to contain active compounds of secondary metabolites that are antibacterial in nature. This study was conducted to determine the ability of soursop seed extract …
The problem of antibiotic resistance has become a worldwide concern and a serious problem. Antibiotic resistance is termed as “silent pandemic”. Methicillin-Resistant Staphylococcus aureus (MRSA) is one type of Staphylococcus aureus (SA) strain that is resistant to beta-lactam antibiotics. This bacterium is responsible for as many as 100,000 deaths due to Antimicrobial Resistance (AMR) in 2…
Infections caused by antibiotic-resistant bacteria, particularly carbapenem-resistant Pseudomonas aeruginosa (CRPA), have become a significant global health issue. Pseudomonas aeruginosa is a common nosocomial pathogen that often demonstrates resistance to many antibiotics. Given the rising cases of antibiotic resistance, alternative treatments are needed, one of which involves utilizing the po…
Tea can be processed into kombucha through a fermentation process. Kombucha is made by fermenting a solution of black tea, sugar and a kombucha culture called SCOBY (Symbiotic Culture of Bacteria and Yeast). One of the innovations in kombucha processing is the combination with avocado seeds (Persea americana Mill.) and bay leaves (Syzygium polyanthum (Wight.)) in the second fermentation. This s…
Kombucha is a fermented beverage of green tea or black tea using SCOBY (Symbiotic Culture of Bacteria and Yeast). Kombucha provides benefits for stimulating the immune system, improving digestive tract function and preventing microbial infections due to the presence of antibacterial compounds. Antibacterial activity can be enhanced by utilizing secondary metabolites in fruits such as apple (Mal…
Research has been carried out regarding the inhibitory power test of ethanol extract of purple golden leaves (Ruellia tuberosa L.) against Pseudomonas aeruginosa bacteria. This research aims to obtain information regarding the effect of ethanol extract of purple golden leaves on P. aeruginosa bacteria and the minimum inhibitory concentration (MIC) of ethanol extract of purple golden leaves on P…
High doses of antibiotics use continously can increase an antibiotic resistance, therefor a research for new antibiotics is needed to reduce the possibility of resistance. Actinomycetes are one of the microorganisms that have commercial value because of their ability to produce antibiotics. 80 % of antibiotics on the market today are produced by Streptomyces. Exploration of Actinomycetes from s…
Tepung maggot BSF (TMB) dan tepung ikan gabus (TIG) memiliki Antimicrobial peptide dan senyawa lain sebagai antibakteri yang bersifat bakterisidal. Penelitian ini dilakukan untuk mengetahui aktivitas antibakteri kombinasi TMB dan TIG terhadap Escherichia coli dan Staphylococcus aureus. Uji aktivitas antibakteri dilakukan dengan mencari Konsentrasi Hambat Minimum (KHM) TMB dan TIG tunggal, Konse…
Staphylococcus aureus bacterial infection is a health threat. Treatment of infections using antibiotics has been widely used. However, misuse of antibiotics can cause resistance. One way to overcome typically by creating common fixings as antibacterials. BSF larvae oil (MLB) and tuna fish oil (MIT) are known to have antibacterial potential. This study aims to determine the antibacterial activit…
Research has been conducted on the activity of sembung leaf ethanol extract (Blumea balsamifera L.) against Pseudomonas aeruginosa bacteria. This study aims to obtain information on the effect of the ethanol extract of sembung (B. balsamifera) leaves on P. aeruginosa bacteria and the minimum inhibitory concentration (MIC) of the ethanol extract of sembung (B. balsamifera) leaves on P. aeruginos…
Background: The failure of endodontic treatment is often caused by errors during elimination procedures of Gram-positive bacteria (Enterococcus faecalis) so that it is necessary to use irrigating solutions such as sodium hypochlorite (NaOCl) to eliminate it from the root canal. Prabumulih City’s pineapple leaves (Ananas comosus) are herbal plants that have antibacterial properties due to the …
Daun sirsak (Annona muricata L.) merupakan tanaman herbal yang dapat dimanfaatkan untuk mengobati penyakit diare. Penelitian ini bertujuan untuk melihat aktivitas ekstrak etanol daun sirsak terhadap pertumbuhan bakteri probiotik Lactobacillus plantarum serta kemampuannya dalam menghambat bakteri patogen Escherichia coli. Metode uji pertumbuhan L. plantarum menggunakan metode Total Plate Count (…
Sungkai leaves (Peronema canescens Jack.) has been used by the community for a long time as a traditional medicine for fever, stomachache, mouth antiseptic, and toothache medicine. This research was conducted to isolate and identify bioactive compounds from endophytic fungi of sungkai leaves. The research was started by isolating and purifying endophytic fungi from fresh sungkai leaves, then id…
Background: Periodontal disease is the second most frequent dental and oral health problem In Indonesia. Porphyromonas gingivalis, prevalent in subgingival plaques, is the primary bacteria that cause periodontal disease. Periodontal disease can be prevented mechanically, chemically, or spontaneously by inhibiting plaque growth. Natural ingredients such as corn hair, which include antibacterial …
Background: Porphyromonas gingivalis is one of the main etiologies in the pathogenesis of periodontal disease found in plaque. Plaque can be controlled using toothpaste. The combination of herbal ingredients and toothpaste can produce complementary effects. Meanwhile, Gambier extract (Uncaria gambir Roxb.) was reported to contain catechin and tannin which act as antibacterial. Objective: The pu…
Backgrounds : Various kinds of preventions have been developed to get healthy periodontal tissues. The antibacterial that contained in natural materials as clinical material has become the new innovations in preventing periodontal disease. Apple skin contains phenolic compounds that are antibacterial, like flavonoids and tannins. Objective : The purpose of this study was to determine the effect…
Cestrum nocturnum leaves have approved to prevent the growth of Streptococcus mutans because i t contains flavonoid Flavonoids are phenolic t hal have abilitv to denaturized protein. The purpose of this study to assess that cestrum nocturnum leaves have antibacterial effect on Streptococcus mutans. The melhod of this research i s laboratory experimental with Pos t Test Only Control design. The …
Tindakan irigasi merupakan salah satu dari triad endodontik yang penting dilakukan untuk mengurangi jumlah mikroorganisme pada infeksi saluran akar. Bahan irigasi yang sering digunakan pada perawatan saluran akar adalah Chlorhexidine 2%, namun dapat juga diperoleh dari tanaman herbal dengan memanfaatkan senyawa aktif yang dimilikinya, misalnya temu putih (Curcuma zedoaria). Rimpang temu putih m…
Salvadora persica merupakan salah satu tanaman produk herbal yang memiliki sifat antibakteri. Miswak memiliki zat aktif berupa salvadorine, benzylsothio-cyanate, saponin, tannin, dan flavonoid yang memiliki aktivitas antibakteri yang signifikan terhadap bakteri Gram positif seperti Enterococcus faecalis. Tujuan penelitian ini adalah untuk mengetahui konsentrasi ekstrak miswak yang efektif terha…
Denture stomatitis adalah proses inflamasi yang terjadi pada mukosa palatum yang penyebabnya adalah bakteri Staphylococcus aureus. mengandung asiaticoside dan flavonoid yang terbukti mempunyai efek antibakteri. Tujuan penelitian ini adalah untuk membuktikan efek antibakteri infusum daun pegagan terhadap pertumbuhan bakteri Staphylococcus aureus penyebab denture stomatitis pada mukosa palatum se…
Introduction: Typhoid fever is still being one of the global medicalyproblem. However, clinicians findany cases of antibiotic-sensitiye resistanceto Salmonella typhi which is the etiology of typhoid fever. In addition, today's emerging tendency for people in selecting herbs to overcome various diseases. The use of seeds of cucumber (Cucumis sativus L.) as an alternative medicine in some gastroi…
Pemberian medikamen saluran akar bertujuan untuk mengeliminasi bakteh yang tidak dapat dihancurkan dengan proses instrumentasi dan irigasi. Enterococcus faecalis merupakan bakteri yang sering ditemukan pada perawatan saluran akar yang gagal dan resisten terhadap Ca(OH). Aloe vera dipilih sebagai alternatifbahan medikamen saluran akar karena mengandung antracpiinon, saponin, dan tanin yang memil…
Background: This research was conducted to know whether betle leaf (Piper belle L.) extract has antibacterial activity against Neisseria gonorrhoeae causing Gonore, to asses The Minimum Inhibitory Concentration (MIC), and to asses its equivalent rate with ciprojloxacin. Methods: This research was designed as experimental laboratory. Betle leaf extract was obtained by multilevel maceration metho…
Vitex pinnata merupakan tumbuhan tropis berasal dari famili Verbenaceae. Penelitian ini bertujuan untuk mengisolasi senyawa metabolit sekunder dan menentukan aktivitas antibakteri kayu batang tumbuhan ini terhadap Staphylococcus aureus ATCC 25923 dan Streptococcus pneumoniae ATCC 49619. Proses pemurnian dilakukan dengan cara ekstraksi (maserasi) menggunakan pelarut metanol destilasi, fraksinasi…
Demam tifoid terus menjadi masalah kesehatan yang utama di banyak negara berkembang di seluruh belahan dunia. Secara global, demam tifoid merupakan penyebab penting morbiditas dan kematian di banyak tempat di dunia, dengan perkiraan 12-33 juta kasus menyebabkan 216.000-600.000 kematian per tahun. Pada beberapa tahun terakhir ini, para klinisi di beberapa negara mengamati adanya kasus demam tifo…