Chayote leaves (Sechium edule (Jacq.) Swartz) contain secondary metabolites like flavonoids, tannins, and saponins acting as antidiabetic agents through beta-cell protection. This study aimed to determine the antidiabetic activity of the ethanolic extract of chayote leaves (EECL) and evaluate its effect on pancreatic histopathology in hyperglycemic male Wistar rats. Hyperglycemia was successful…
Type II Diabetes Mellitus is a non-communicable disease closely associated with dietary patterns and physical activity. This study aims to determine the relationship between dietary patterns and physical activity with random blood glucose levels among Type II Diabetes Mellitus patients at Balai Agung Health Center, Sekayu. The study employed a quantitative method with a cross-sectional design. …
Background: Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia resulting from impaired insulin secretion or insulin resistance, with chronic low-grade inflammation playing a role in its pathogenesis. Diacerein has anti-inflammatory effects and improves insulin sensitivity; however, clinical evidence in Indonesia remains limited. Objective: To evaluate the effect of adding diacere…
The ability to do Self Care Management in patients with type 2 DM is low due to poor family support. Many family members in today's era of progress who are busy with their work cause people with type 2 DM if there are problems that are not paid attention to and feel burdensome to the family because of the disease experienced. Doing Self Care Management is very important because it can improve t…
Background: Semaglutide is a GLP-1 receptor agonist used as a therapy to improve glycemic control in patients with Type 2 Diabetes Mellitus. Although its use continues to increase globally, data regarding the utilization pattern of this drug in Indonesia, remains scarce. Objective: To determine the pattern of semaglutide use among T2DM patients at Siloam Sriwijaya Hospital Palembang from Januar…
Background: Diabetic foot ulcer is a serious complication of diabetes mellitus that can lead to amputation and increase morbidity and mortality rates. PEDIS (Perfusion, Extent, Depth, Infection, Sensation) Score is a classification system developed by the International Working Group on the Diabetic Foot (IWGDF) to assess the severity of diabetic foot ulcers and predict prognosis. This study aim…
Background: Diabetes mellitus (DM) is a chronic disease with an increasing prevalence on a global scale, including in Indonesia. Based on the International Diabetes Federation (IDF) data, Indonesia ranks fifth in the world in terms of the number of people living with diabetes. In 2021, there were an estimated 19.5 million individuals with diabetes in Indonesia, a figure that is predicted to rea…
Obesitas merupakan suatu kelainan metabolisme yang paling lama tercatat dalam sejarah, mulai sejak jaman Mesir dan Yunani purba, bahkan hingga sekarang keadaan ini telah menjadi suatu permasalahan serius. Masyarakat sering tidak menganggap obesitas sebagai suatu penyakit tetapi justru merupakan sesuatu yang wajar bahkan dianggap sebagai suatu tanda kemakmuran. Padahal, sebenarnya obesitas mempu…
Background: Type 2 Diabetes Mellitus (DM) is a disease characterized by elevated blood sugar levels due to insulin resistance or inadequate insulin production. Management of Type 2 DM in hospitals only focuses on pharmacological and dietary therapy, while physical activity is still not optimized. One of the physical activities that can be done in Type 2 DM patients is progressive muscle relaxat…
The prevalence of diabetes mellitus continues to increase in Indonesia. Individuals considered at high risk for diabetes mellitus are likely to experience anxiety, which is an individual response to worry about unpleasant thoughts. Anxiety management in this study used peer support groups. This study aimed to determine the effect of peer support group interventions on anxiety levels in a high-r…
Diabetes mellitus is a metabolic disease characterized by hypoglycemia and hyperglycemia. However, this is often not realized by various communities due to lack of information and sufficient knowledge and self-care and compliance to detect early the risk of complications and prevention and 4 improve the quality of life of DM sufferers so that complications do not occur, especially complications…
Diabetes mellitus is a metabolic disorder characterized by elevated blood glucose levels. Diabetes mellitus has become one of the major health issues with a steadily increasing prevalence in Indonesia. Due to its significant impact, diabetes mellitus has become a primary focus in the medical field. Over the years, animal experiments have been conducted to study diabetes mellitus and evaluate an…
Background: Diabetic Retinopathy (DR) is a microvascular complication of Diabetes Mellitus (DM) that can lead to visual impairment and blindness. The severity of DR is often correlated with decreased visual acuity, but other factors such as age, gender, intraocular pressure, glycemic control, hypertension, and the presence of macular edema may also contribute. This study aims to analyze the rel…
Diabetes mellitus emergencies are critical conditions related to acute complications of diabetes mellitus that are life-threatening risk and require immediate treatment. Prevention of diabetes mellitus emergencies can be done by increasing patient knowledge. This study aims to determine the effect of education using leaflet media on patient knowledge about diabetes mellitus emergencies. This st…
Background. Streptozotocin (STZ) is a diabetogenic compound used to induce diabetes mellitus (DM) in animal models. A dose of 45–65 mg/kgBW of STZ triggers the destruction of pancreatic beta cells, resulting in a more stable hyperglycemic condition. Hyperglycemia, as a common feature of DM, leads to metabolic disturbances that cause oxidative stress and dyslipidemia. STZ at a dose of 60 mg/kg…
Diabetes mellitus (DM) is a life-threatening chronic disease. Death due to hypoglycemia and hyperglycemic crisis can occur if patients lack adequate knowledge. This study aims to determine the overview of type 2 diabetes mellitus patients' knowledge about hypoglycemia and hyperglycemic crisis. The method used in this study was quantitative with a descriptive analytical design and a survey appro…
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease with a high prevalence that requires HbA1c control as an indicator of blood glucose stability, where patient adherence plays a crucial role in its management. This study aimed to identify the effect of patient adherence on HbA1c levels at RSI Siti Khadijah Palembang. It was an analytical observational study conducted prospectively u…
Diabetes mellitus (DM) can cause cognitive disorders and even Alzheimer's disorders. Catechins in gambier have pharmacological effects as antioxidants and can be used as therapy to improve cognitive function and prevent Alzheimer's disease. The research aims to determine the characteristics of gambier extract and SNE as active anti-diabetic ingredients to prevent Alzheimer's disease and to dete…
Background: The increasing cases of diabetes in Indonesia must be addressed through strategies to improve health services. Improving health services requires an assessment of the quality of health services. The quality of health services can be assessed based on the patient's re-visit interest. Assessment of the quality of diabetes services can be seen from the aspects of characteristics, under…
Introduction: Tuberculosis is an infectious disease caused by infection with mycobacterium tuberculosis bacteria. A person with a history of diabetes mellitus has a 3 times greater risk of developing tuberculosis than a person without diabetes mellitus. This study was conducted by the author to analyze the relationship between type 2 diabetes mellitus and the severity index of chest radiographs…
Introduction: Diabetic retinopathy is a complication that occurs in patients with type 1 or type 2 diabetes mellitus and is a major cause of vision loss. In proliferative diabetic retinopathy there are abnormal blood vessels in the retina. Patient with proliferative diabetic retinopathy can experience bleeding (vitreous hemorrhage) or retinal detachment, which can lead to blindness. To restore …
Background: Diabetes mellitus is a chronic disorder occurring when the body cannot produce enough insulin hormone or use it effectively, leading to an increase in blood sugar levels. Uncontrolled diabetes mellitus can result in various complications, one of which is diabetic foot ulcers. Various risk factors influence the occurrence of diabetic ulcers, including self-foot care. This study aims …
Background: Indonesia ranks 7th out of 10 countries in the world with the highest number of people with diabetes. In type 2 DM TNF-α contributes to the development of insulin resistance, which accounts for 90-95% of cases of this disease. Karamunting (Rhodomyrtus tomentosa) is one of the plants that has medicinal value, with more than 100 compounds, Quercetin is one of the compounds that has a…
Background: The causative germ of diabetic foot infections are highly diverse and are usually treated with antibiotics. Inappropriate use of antibiotics can influence germs to become resistant and result in increased severity and mortality. Study on the distribution of germs and their sensitivity is rarely conducted in Palembang. Some studies only identify 1 type of germ so it does not describe…
Background : Indonesia was ranked 5th worldwide regarding diabetic patients with a total number of 19,5 millions, and is expected to increase by around 21.3 millions by 2045. 90% of the case is a Type 2 Diabetes Mellitus that were caused by insulin resistance, which can be triggered by IL-6. Karamunting (Rhodomyrtus tomentosa) is a plant that often be used as a herbal medicine. Quercetin is one…
Stroke is the second reason for death and third reason for disability in the world. Stroke used to be called as a disease for old people, but as the increase of risk behavior that the young people do made an increase for incidence of stroke in young people. This study aim to analyze the relationship between diabetes mellitus and the incidence of stroke in productive age in D.I. Yogyakarta provi…
Healthy visits can reduce the risk of complications in people with Diabetes Mellitus and minimize the burden of health financing. The utilization of sick visits still outweighs healthy visits in Indonesia. This study aims to analyze the demographic and socioeconomic factors associated with the utilization of healthy visits in by Diabetes Mellitus patients Indonesia. This research was a quantita…
Diabetes mellitus is a metabolic disorder characterized by high sugar levels (hyperglycemia). Diabetic foot ulcers (UKD) are one of the most common complications of type 2 diabetes mellitus. UKD is a complication of diabetes mellitus in the form of a full-thickness wound that is distal to the ankle caused by peripheral neuropathy. In Indonesia, the prevalence of UKD sufferers is around 15%, the…
Diabetes melitus (DM) tipe 2 merupakan salah satu penyakit kronis yang banyak diderita oleh masyarakat terutama pada lansia dan dapat menurunkan kualitas hidup. Pada penderita DM tipe 2 kualitas hidup yang rendah dapat memperburuk kondisi penyakitnya. Oleh karena itu, kualitas hidup yang baik bagi penderita DM tipe 2 sangat dibutuhkan untuk mengelola penyakit dan menjaga kesehatannya sehingga m…
Latar belakang : Diabetes mellitus ialah keadaan dimana kadar gula darah meningkatan akibat terganggunya sekresi insulin, kerja insulin atau keduanya dan menyebabkantimbulnya bebagai komplikasi baik makrovaskular maupun mikrovaskular. Komplikasi mikrovaskuler yang umumnya timbul yakni tukak diabetik. Penderita diabetes mellitus juga mengeluhkan nyeri kronis akibat dari dari tukak diabetik, teng…