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EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN BRONKOPNEUMONIA PEDIATRI DENGAN ME…
The irrationality of high-use antibiotics for infectious diseases can cause the result of failing to achieve therapeutic goals. One of these contagious diseases is bronchopneumonia, a condition with inflammation in the lungs marked by infiltrate spots around the bronchi. Bronchopneumonia is one of the leading infectious causes of death in children under five. This study aims to examine and eval…
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- xix, 83 hlm.; Ilus.; 29 cm
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- T949902023
UJI AKTIVITAS EKSTRAK ETANOL DAUN SIRSAK (Annona muricata L.) TERHADAP PERTUM…
Daun sirsak (Annona muricata L.) merupakan tanaman herbal yang dapat dimanfaatkan untuk mengobati penyakit diare. Penelitian ini bertujuan untuk melihat aktivitas ekstrak etanol daun sirsak terhadap pertumbuhan bakteri probiotik Lactobacillus plantarum serta kemampuannya dalam menghambat bakteri patogen Escherichia coli. Metode uji pertumbuhan L. plantarum menggunakan metode Total Plate Count (…
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- xi, 122 hlm.; Ilus.; 29 cm
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- T952382023
FORMULASI DAN ANALISIS MIKROBIOLOGIS LIPSTIK CAIR DENGAN PENGAWET ALAMI CHITO…
Liquid lipstick is a cosmetic type of lip color that is currently in great demand by consumers. Repeated use of liquid lipstick can cause the growth of pathogenic microbes such as Staphylococcus aureus and Candida albicans. Chitooligosaccharide is a derivative of chitosan resulting from the deacetylation of chitin and has been widely reported to have biological activity as an antimicrobial. Thi…
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- xix, 119 hlm.; Ilus.; 29 cm
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- T950142023
OPTIMASI DAN KARAKTERISASI FORMULA SEDIAAN TRANSETOSOM KLINDAMISIN HCL DENGAN…
Klindamisin HCl adalah golongan obat antibiotik kelas III dimana solubilitasnya tinggi sedangkan permeabilitasnya rendah berdasarkan Biopharmaceutical Classification System. Formulasi topical konvensional menggunakan antibiotic tersebut akan mengalami kendala yang disebabkan dari permeabilitasnya yang buruk sulit untuk menembus lapisan kulit stratum kornuem. Hal ini menghambat klindamisin hcl u…
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- xvii, 88 hlm.; Ilus.; 29 cm
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- T1047762023
UJI AKTIVITAS GASTROPROTEKTIF EKSTRAK ETANOL RIMPANG TEMU IRENG (Curcuma aeru…
Ethanol extract of temu ireng rhizome (Curcuma aeruginosa Roxb.) contains many efficacious secondary metabolites, one of which is flavonoid, phenolic, and curcuminoid. The compound is thought to have the potential to be gastroprotective. This research aimed to determine the effect of differences in the dose of ethanol extract of temu ireng rhizome as gastroprotective on the evaluation parameter…
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- xvii, 106 hlm.; Ilus.; 29 cm
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- T1047642023
AKTIVITAS PREBIOTIK TEPUNG PISANG KEPOK (MUSA PARADISIACA FORMATYPICA) TERHAD…
Kepok banana (Musa paradisiaca formatypica) contains inulin and fructooligosaccharide (FOS) which act as natural prebiotics. This research was conducted to analyze the effect of kepok banana flour before and after modification with high pressure heating on the growth of L. plantarum using Design Expert 12®. Test standardization of the quality of banana flour kepok based on SNI 01-3751-2009. Mo…
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- xvii, 108 hlm.; Ilus.; 29 cm
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- T920912023
FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SUBMIKRO PARTIKEL EKSTRAK DAUN GINSEN…
Javanese ginseng leaves (Talinum paniculatum (Jacq.) Gaertn) contains flavonoid compounds, one of which is quercetin as an antibacterial. This study aims to determine the variation in calcium chloride concentration as a crosslinker against the submicro particles produced and determine its antibacterial ability compared to Javanese ginseng leaf extract without polymers. Making submicro particles…
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- xix, 66 hlm.; Ilus.; 29 cm
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- T1262682023
FORMULASI DISPERSI PADAT AZITROMISIN DENGAN KITOSAN DAN NATRIUM ALGINAT MENGG…
Azithromycin is a macrolide-derived antibiotic compound that is poorly water soluble. Various technologies are reported to overcome the solubility problem of poorly soluble drugs, one of which is solid dispersion technology. Solid dispersion refers to a group of solid products consisting of at least two different components, generally a hydrophilic matrix and a hydrophobic drug. Solid dispersio…
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- xix, 74 hlm.; Ilus.; 29 cm
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- T1220722023
FORMULASI GEL TABIR SURYA EKSTRAK ETANOL DAUN MAWAR (ROSA CHINENSIS JACQ.) SE…
Sunscreen is a cosmetic product that physically and chemically can prevent the penetration of UV ray into the skin. Rose leaves (Rosa chinensis Jacq.) have potential of being sunscreen because it contains phenolic, flavonoid and tannin compounds that have the ability to absorb UV ray. The formulation of sunscreen gel is conducted using the combination of HPMC and carbopol as a gelling agent. Th…
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- xv, 115 hlm.; ilus.; 29 cm
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- T915812023
MODIFIKASI TEPUNG BIJI NANGKA (Artocarpus heterophyllus) DAN PENENTUAN INDEKS…
Nangka (Artocarpus heterophyllus) pada bijinya mengandung senyawa oligosakarida yang dapat berperan sebagai prebiotik alami dengan kadar yang rendah, sehingga perlu dimodifikasi untuk meningkatkan sifat prebiotiknya. Penelitian ini bertujuan untuk mengetahui pengaruh modifikasi tepung biji nangka dengan fermentasi menggunakan L. plantarum dan autoclaving-cooling 3 siklus terhadap pertumbuhan L.…
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- xvii, 124 hlm.; Ilus.; 29 cm
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- T1061002023
EVALUASI PENGGUNAAN ANTIBIOTIKA PADA PASIEN INFEKSI SALURAN KEMIH MENGGUNAKAN…
Urinary tract infection is an infection of microorganism in the urinary tract including the urethra, bladder, ureters, or kidneys. The main treatment for UTIs is antibiotics. The high use of antibiotics related to UTI will increase the incidence of antibiotic resistance so that the clinical desired is not achieved. Antibiotic resistance control is needed one of which is to evaluate the use of a…
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- xix, 99 hlm.; Ilus.; 29 cm
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- T1039982023
EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN PNEUMONIA DEWASA DI INSTALASI RAWA…
Ketidakrasionalan obat akan memunculkan berbagai efek samping, biaya pengobatan yang mahal, serta resistensi terhadap pemakaian antibiotik. Pneumonia merupakan infeksi di jaringan paru yang disebabkan oleh berbagai mikroorganisme, seperti bakteri, virus, parasit, jamur, pajanan bahan kimia atau kerusakan fisik paru. Terapi utama yang diberikan pada pasien pneumonia adalah antibiotik. Meningkatn…
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- xviii, 61 hlm.; Ilus.; 29 cm
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- T1046012023
PENGARUH PEMBERIAN FRAKSI ETANOL DAUN UBI JALAR UNGU TERHADAP ALIRAN DAN PARA…
Purple sweet potato leaves contain alkaloids, flavonoids, quinones, steroids, monoterpenes, sesquiterpenes, polyphenolics and tannins which are anti-atherosclerotic. This study aims to determine the effect of giving the ethanol fraction of purple sweet potato leaves on rat blood flow and coagulation factors and its effect on the histopathological picture of the rat aorta induced by high-fat sup…
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- xviii, 104 hlm.; ilus.; 29 cm
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- T890992023
UJI KADAR FENOLIK TOTAL DAN AKTIVITAS ANTIOKSIDAN SECARA IN-VITRO PADA TANAMA…
Research has been carried out on the anti-oxidant potence of kecombrang (Etlingera elatior), which includes the determination of total phenolic content and antioxidant activity of the extract, and the fractions of the kecombrang (E.elatior) plant. Determination of total phenolic content with gallic acid standard using Follin Ciocalteu reagent. The principle of this test is the formation of a bl…
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- xvii, 115 hlm.; ilus.; 29 cm
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- T891462023
UJI AKTIVITAS EKSTRAK ETANOL DAUN KARDIA (Bellucia pentamera Naudin) TERHADAP…
Luka terbuka merupakan luka yang mengakibatkan kerusakan pada kulit jika diabaikan akan terjadi infeksi. Tanaman obat yang telah diteliti dan dimanfaatkan untuk penyembuhan luka terbuka salah satunya yaitu daun kardia (Bellucia pentamera Naudin). Daun kardia (Bellucia pentamera Naudin) mengandung senyawa flavonoid, saponin, tannin, fenolik, dan triterpenoid sebagai antijamur, antivirus, antibak…
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- xviii, 98 hlm.; ilus.; 29 cm
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- T887462023
OPTIMASI DAN KARAKTERISASI ETOSOM BINER KLINDAMISIN HCL DENGAN VARIASI ETANOL…
Klindamisin HCl memiliki masalah formulasi secara topikal yang menyebabkan penetrasi obat ke dalam kulit kurang optimal dalam mengatasi bakteri penyebab jerawat. Klindamisin HCl yang digunakan secara topikal dengan kadar 1% tetapi rata-rata hanya 4% sampai 5% klindamisin yang diserap ke dalam kulit sehingga diperlukan penggunaan berulang untuk mencapai efeknya. Etosom biner klindamisin HCl dapa…
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- xvii, 88 hlm.; ilus.; 29 cm
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- T889712023
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAN FRAKSI DAUN PUCUK IDAT (Cratoxyl…
Daun pucuk idat mengandung metabolit sekunder yaitu flavonoid, saponin, tanin, triterpenoid, steroid, dan fenolik yang memiliki aktivitas farmakologi sebagai antioksidan. Penelitian ini bertujuan untuk mengetahui karakteristik ekstrak etanol, pengaruh pemberian ekstrak etanol dan fraksi daun pucuk idat terhadap aktivitas antioksidan dengan mengukur kadar MDA, penentuan aktivitas enzim katalase,…
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- xxi, 142 hlm.; ilus.; 29 cm
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- T887122023
UJI AKTIVITAS ANTIHIPERLIPIDEMIA FRAKSI ETIL ASETAT DAUN UBI JALAR UNGU (Ipom…
The ethyl acetate fraction of purple sweet potato leaves contains secondary metabolites of flavonoids, tannins, and phenols, which are thought to have antihyperlipidemic activity. The aim of this study was to determine the antihyperlipidemic activity of the ethyl acetate fraction of purple sweet potato leaves in male albino rats by measuring total cholesterol, triglycerides, HDL and LDL, as wel…
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- xix, 130 hlm.; ilus.; 29 cm
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- T890982023
UJI AKTIVITAS ANTIHIPERLIPIDEMIA FRAKSI N-HEKSANA DAUN UBI JALAR UNGU ( Ipomo…
Purple sweet potato (Ipomoea batatas (L.) Lam.) leaf contain beta carotene compounds which have antihyperlipidemia activity. This study aims to determine the antihyperlipidemia effect of n-hexane fraction of purple sweet potato leaves on total cholesterol, triglyceride, HDL and LDL levels in rat serum induced by PTU and high fat supplements. This study divided into 6 groups, normal group, posit…
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- xix, 121 hlm.; ilus.; 29 cm
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- T891002023
OPTIMASI KECEPATAN DAN LAMA PENGADUKAN TERHADAP KARAKTERISASI ETOSOM KLINDAMI…
Clindamycin HCl has problem of penetration into the skin, only 1% to 3% of the applied dose of clindamycin HCl can be absorbed into the skin for 24 hours so that ethosomes are expected to be a delivering clindamycin HCl in penetration into the skin with the ability to fusion with skin lipids and high deformability. This study aims to optimize the ethosomes formula for clindamycin HCl with varia…
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- xvi, 100 hlm.; ilus.; 29 cm
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- T890402023
EFEK PEMBERIAN SNACK BAR EKSTRAK DAUN PEGAGAN (Centella asiatica L.) KOMBINAS…
Gotu Kola (Centella asiatica L.) and gambier (Uncaria gambir Roxb.) is a plant that is believed to have many benefits. The high antioxidant content, especially flavonoids, triterpenoids, polyphenols, saponins from gotu kola and gambier leaves are believed to improve memory. This study aims to determine the levels of flavonoids, levels of proximate snack bar characteristics , and to determine th…
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- xix, 98 hlm.; ilus.; 29 cm
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- T887982023
UJI AKTIVITAS ANTIDIARE FRAKSI ETIL ASETAT DAUN KETEPENG CINA (Cassia alata L…
Chinese ketepeng leaves contain active compounds of alkaloids, saponins, tannins, steroids, anthraquinones, and flavonoids as antibacterials. This study aims to determine the antidiarrheal activity of the ethyl acetate fraction of Chinese ketepeng leaves induced by Escherichia coli bacteria. This research was conducted by experimental method. The treatment group was divided into seven groups: n…
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- xix, 134 hlm.; ilus.; 29 cm
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- T888722023
PROFIL STRES OKSIDATIF DAN MIKROANATOMI OTAK PEMBERIAN SELF-NANOEMULSIFYING D…
Stres oksidatif dapat menimbulkan kerusakan DNA sehingga dapat menurunkan fungsi kognitif. Katekin pada teh putih memiliki efek farmakologis sebagai antioksidan dapat dijadikan terapi peningkatan fungsi kognitif. Penelitian bertujuan untuk mengetahui nilai profil stres SOD, CAT, dan MDA serta mengetahui gambaran histopatologi hippokampus dan sel neuron. Penelitian menggunakan rancangan post tes…
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- xv, 93 hlm.; ilus.; 29
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- T890102023
PENGARUH PEMBERIAN FRAKSI N-HEKSAN DAUN UBI JALAR UNGU TERHADAP ALIRAN DAN PA…
Daun ubi jalar ungu (Ipomoea Batatas (L.) Lam.) mengandung senyawa beta-karoten yang memiliki efek farmakologis sebagai antiaterosklerosis. Penelitian ini bertujuan untuk melihat aktivitas fraksi n-heksan daun ubi jalar ungu dalam mengembalikan aliran dan faktor koagulasi darah tikus serta pengaruhnya terhadap gambaran histopatologi aorta tikus yang diinduksi suplemen tinggi lemak. Pada penelit…
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- ix, 95 hlm.; ilus.; 29 cm
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- T890962023
UJI AKTIVITAS ANTIOKSIDAN SEDIAAN NANOEMULSI MINYAK BIJI RAMI (Linum usitatis…
Flaxseed oil (Linum usitatissimum) has been shown to enhance the function of the antioxidant system due to its antioxidant compounds such as phenols and vitamin E. The development of flaxseed oil into stable dosage forms such as nanoemulsions is very potential from the point of view of the efficacies contained. This research was conducted to determine the concentration of flaxseed oil in nanoem…
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- xviii, 94 hlm.; ilus.; 29 cm
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- T893412023
UJI AKTIVITAS ANTIOKSIDAN SEDIAAN NANOEMULSI MINYAK SACHA INCHI (Plukenetia v…
Minyak Sacha Inchi (Plukenetia Volubilis L.) mengandung senyawa bioaktif yang bersifat antioksidan diantaranya yaitu flavonoid dan beberapa asam lemak tinggi yakni asam palmitat, asam stearat, asam oleat, asam linoleat, dan asam linolenat. Penelitian ini bertujuan untuk menentukan konsentrasi minyak sacha inchi dalam sediaan nanoemulsi yang memiliki aktivitas antioksidan terbaik kemudian dianal…
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- xvii, 84 hlm.; ilus.; 29 cm
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- T893252023
PENGARUH PEMBERIAN FRAKSI ETIL ASETAT DAUN UBI JALAR UNGU TERHADAP ALIRAN DAN…
Purple sweet potato leaves are plants that contain secondary metabolites of flavonoids, tannins and phenolics which are proven to have activity as a vasodilator and are able to increase the formation of Nitric Oxide (NO) as so as reducing atherosclerosis. The purpose of this study was to determine the effect of giving the ethyl acetate fraction of purple sweet potato leaves on blood flow and bl…
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- iv, 60 hlm.; ilus.; 29 cm
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- T890662023
PENGARUH PEMBERIAN ORALLY DISSOLVING FILM EKSTRAK BUAH MENGKUDU (Morinda citr…
Noni fruit (Morinda citrifolia L.) contains flavonoids that have immunomodulatory activity. Orally Dissolving Film (ODF) formulation removes the bitter taste and low bioavailability of extract. This study aims to determine the characteristics of ODF noni fruit extract and the immunomodulatory effects of ODF noni fruit extract in Wistar male rats induced by E. coli on the number of leukocytes, l…
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- xviii, 135 hlm.; ilus.; 29 cm
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- T1141362023
UJI EFEK ANTIULCER EKSTRAK ETANOL RIMPANG TEMU MANGGA (Curcuma amada Roxb.) T…
Rimpang temu mangga (Curcuma amada Roxb.) mengandung metabolit sekunder seperti flavonoid, kurkuminoid dan fenolik yang berpotensi memiliki aktivitas antiulcer. Penelitian ini bertujuan untuk mengetahui efek antiulcer ekstrak etanol rimpang temu mangga (EERTM) yang diinduksi etanol absolut. Efek antiulcer ini dilihat dari parameter seperti, evaluasi lesi lambung, pengukuran volume, pH, keasaman…
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- xv, 102 hlm.; ilus.; 29 cm
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- T1044952023
FORMULASI EKSTRAK DAUN GAMBIR (UNCARIA GAMBIR ROXB.) SEBAGAI KOSMETIK PEMBERS…
Catechins are flavonoid compounds that contain antioxidants that can prevent cell damage from free radicals and reduce excess melanin production by inhibiting the tyrosinase enzyme. Delivery of active substances is more effective when done in dosage forms, so gambir extract is formulated into facial cleansers that can deliver active substances properly. This study aims to obtain an optimum form…
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- xix, 101 hlm.; ilus.; 29 cm
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- T1050322023
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