Obat tradisional adalah bahan atau ramuan bahan berupa bahan tumbuhan, bahan hewan, bahan mineral, sediaan sarian, atau campuran dari bahan-bahan tersebut yang secara turun-temurun telah digunakan untuk pengobatan dan diterapkan sesuai dengan norma yang berlaku di masyarakat. Obat tradisional disebut juga obat alternatif, obat alamiah, atau obat herbal yang sudah dimanfaatkan sejak lama. Pengo…
Background: Several treatments in dentistry often can cause wounds, especially to the gingiva. Corn hair is a natural ingredient that is used as an alternative in the treatment of wounds. Several studies have stated that corn hair content such as flavonoids, saponins, and tannins can accelerate wound healing, but their effect on the fibroblasts in gingival wound healing is not yet known. Object…
Tepung biji teratai mengandung rafinosa yang berpotensi sebagai prebiotik. Penelitian ini bertujuan untuk mengetahui efek prebiotik, indeks prebiotik, serta aktivitas prebiotik tepung biji teratai sebelum modifikasi dan sesudah modifikasi dengan lama waktu fermentasi serta suhu bertekanan tinggi terhadap pertumbuhan L. bulgaricus dalam menghambat pertumbuhan E. coli. Dilakukan uji standarisasi …
Daun sambiloto (Andrographis paniculata (Burm f.) Wall. ex Nees) mengandung senyawa terpenoid utama berupa andrografolid dan senyawa flavonoid berupa kuersetin yang memiliki potensi sebagai agen fotoprotektif. Pembuatan nanoemulsi ekstrak daun sambiloto dilakukan untuk meningkatkan bioavailabilitas, tampilan serta stabilitas ekstrak. Penelitian ini bertujuan untuk mengetahui konsentrasi optimum…
Biji durian memiliki kandungan pati yang dapat dimanfaatkan dalam bentuk pati resisten sebagai prebiotik. Penelitian ini dilakukan untuk memodifikasi tepung biji durian menjadi pati resisten (RS3). Analisis dilakukan terhadap tepung biji durian tanpa modifikasi dan modifikasi dengan fermentasi menggunakan L. plantarum dan 3 siklus autoclaving-cooling terhadap pertumbuhan L. bulgaricus. Karakter…
Purple sweet potato (Ipomoea batatas L.) is a traditional medicine whose safety needs to be tested, one of which is the subchronic test. Purple sweet potato contains secondary metabolites in the form of flavonoids which have pharmacological activity as an anti-inflammatory. This study aims to determine the effect of subchronic toxicity of the ethanol fraction of (Ipomoea batatas L.) leaves on m…
The content in kaffir lime leaf essential oil is proven to have antibacterial properties that can inhibit the growth of Staphylococcus aureus bacteria that cause body odor. The purpose of this study was to make a deodorant lotion from the active ingredient kaffir lime leaf essential oil and to perform antibacterial testing against Staphylococcus aureus. Deodorant lotion made with different conc…
Javanese ginseng leaves (Talinum paniculatum (Jacq.) Gaertn) contains flavonoid compounds, one of which is quercetin as an antibacterial. This study aims to determine the variation in calcium chloride concentration as a crosslinker against the submicro particles produced and determine its antibacterial ability compared to Javanese ginseng leaf extract without polymers. Making submicro particles…
Nangka (Artocarpus heterophyllus) pada bijinya mengandung senyawa oligosakarida yang dapat berperan sebagai prebiotik alami dengan kadar yang rendah, sehingga perlu dimodifikasi untuk meningkatkan sifat prebiotiknya. Penelitian ini bertujuan untuk mengetahui pengaruh modifikasi tepung biji nangka dengan fermentasi menggunakan L. plantarum dan autoclaving-cooling 3 siklus terhadap pertumbuhan L.…
The ethyl acetate fraction of purple sweet potato leaves contains secondary metabolites of flavonoids, tannins, and phenols, which are thought to have antihyperlipidemic activity. The aim of this study was to determine the antihyperlipidemic activity of the ethyl acetate fraction of purple sweet potato leaves in male albino rats by measuring total cholesterol, triglycerides, HDL and LDL, as wel…
Purple sweet potato (Ipomoea batatas (L.) Lam.) leaf contain beta carotene compounds which have antihyperlipidemia activity. This study aims to determine the antihyperlipidemia effect of n-hexane fraction of purple sweet potato leaves on total cholesterol, triglyceride, HDL and LDL levels in rat serum induced by PTU and high fat supplements. This study divided into 6 groups, normal group, posit…
Daun ubi jalar ungu mengandung senyawa flavonoid yang bersifat antioksidan, berfungsi menghambat sintesis kolesterol.Penelitian ini bertujuan untuk mengetahui pengaruh pemberian dosis fraksi etanol daun ubi jalar ungu (Ipomoea Batatas (L.) Lam.) dalam menurunkan kadar trigliserida, kolesterol total, LDL (Low density lipoprotein) dan meningkatkan kadar HDL (High density lipoprotein) darah pada t…
Penyakit kulit merupakan infeksi yang bisa terjadi pada segala usia, salah satunya yang banyak dikeluhkan pada remaja yaitu jerawat. Jerawat dapat disebabkan oleh bakteri seperti P. acnes, Staphylococcus aureus, dan Pityroporum sp. Daun ubi jalar ungu (ipomoea batatas (L.)Lamk) mengandung senyawa flavonoid yang memiliki aktivitas antibakteri dengan salah satu mekanismenya yaitu menghambat sinte…
Minyak Atsiri rimpang temu kunci mempunyai sifat antimikroba yang baik,tetapi mempunyai aroma sangat menyengat.Minyak Atsiri peppermint mempunyai aroma yang lebih lembut,tetapi mempunyai sifat antimikroba yang berbeda dengan minyak atsiri temu kunci. Penelitian ini bertujuan untuk mengetahui potensi antijamur dari kombinasi minyak atsiri rimpang temu kunci dan peppermint terhadap penggunaan tun…
Red spinach leaves contain anthocyanins which have pharmacological effects as antioxidants. The purpose of this study was to extract anthocyanin compounds from red spinach leaves using the UAE (Ultrasonic Assisted Extraction) technique. The optimization of ultrasonic extraction of red spinach leaves aims to determine and find out the extraction temperature, extraction time and pH of the best so…
Hibiscus flower contains anthocyanin secondary metabolites which have pharmacological effects as antioxidants. The purpose of this study was to determine the optimal temperature, time, and concentration of the extraction solvent based on the determination of yield, total anthocyanin content and IC50 antioxidant activity.The research was conducted by varying the temperature (25, 42.5, 60), time …
Cempedak bark (Artocarpus champeden) contains several secondary metabolites which are thought to be effective as hepathoprotectors. This research is conducted to gather the knowledge about cempedak bark ethanol extract activity as hepathoprotector using SGOT and SGPT concentration also from Wistar-hereditary male white mice. Mice are divided into six groups that are normal control, positive gro…
Nanoemulsion is a stable drug delivery system. The preparation of nanoemulsion of basil essential oil was carried out to increase the stability and bioavailability of basil essential oil and to increase its antibacterial effect. This study aims to compare the 3% basil essential oil nanoemulsion and 3% basil leaf essential oil which was not formulated in nanoemulsion on the activity of Staphyloc…
One of the most common skin diseases in the world is acne, which occurs in about 91% of men and 79% of women in their teens. One way in acne therapy is to use an antibacterial to suppress the growth of normal bacterial flora that causes excessive acne. The use of antibiotics for acne is not recommended because it is feared that resistance will occur if they are used continuously. Citronella ess…
The mangosteen rind (Garcinia mangostana L.) contains xanthone derivative compounds including alpha mangosteen which acts as an antityrosinase. A delivery system such as phytosomes can be added to increase the active substance's penetration. The study aimed to determine the optimum formula for phytosomes with variations in phospholipone 90G and cholesterol. Phytosomes were made using the thin l…
Apigenin is the main flavonoid compound that has activity as a vasodilator that can increase hair growth. Flavonoid content in celery leaf extract was 49.83 mg/g with Rf value at TLC of 0.77. This study aims to determine the effect of variations in the concentration of sodium alginate of each formula of 1.6 mg; 3.2 mg and 4.8 mg on the resulting nanoparticles. The manufacture of nanoparticles w…
Silver particles have antibacterial properties. The antibacterial ability of silver particles is influenced by the physical characteristics of the particles such as size, shape, and surface properties. In the synthesis of silver using the green synthesis method by utilizing the ethanol extract of Japanese papaya leaves (Cnidoscolus aconitifolius). Japanese papaya leaves (Cnidoscolus aconitifoli…
Kersen plant (Muntingia calabura L. (Linn)) has been widely used by the community for natural medicine. Cherry leaves contain flavonoid compounds, tannins, saponins, steroids and triterpenoids that can be used as antibacterial, antioxidant, anti-inflammatory, and antidiarrheal. Salmonella typhi is one of the pathogenic bacteria that causes digestive tract infections and causes diarrhea. The aim…
Luka terbuka berpotensi menjadi luka kronis apabila tidak segera ditangani. Eco-enzyme kulit buah jeruk peras mengandung aktivitas enzim protease, asam organik yaitu asam asetat dan metabolit sekunder seperti tanin dan saponin yang berperan sebagai antibakteri dan antiinflamasi. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian sediaan gel eco-enzyme kulit buah jeruk peras terhadap p…
Free radicals in the body can cause various degenerative diseases such as cancer, rheumatism and diabetes, to protect the body from the effects of free radicals, an antioxidant compound is needed. This study aimed to determine the antioxidant activity, total flavonoid content, total phenolic content and characterization of the seed and leaf fractions of avocado (Persea Americana Mill), asoka le…
The stability of flavonoid in pegagan leaf extract is not good due to flavonoid compunds that are easily degraded at high temperatures. Pegagan leaf extract (Cantella asiatica L.) has a high flavonoid content and also has potential as an antioxidant to brighten the skin. Flavonoid stability can be enhanced by making it in the form of submicro particles. This study aims to formulate submicro par…
Silver nanoparticles have been widely used because of their antibacterial activities. However, the synthesis of silver nanoparticles still uses physical and chemical methods that are not eco-friendly. Therefore, green synthesis of silver nanoparticles was carried out by utilizing the ethanol extract of unripe areca nut which is more eco-friendly. The unripe areca nut contains high levels of fla…
Papaya leaves (Carica papaya L.) contain alkaloid and flavonoid compounds that can be used as acne treatment. Pell-off mask is one of the alternative preparations that can increase the comfort of use. This study aims to make a peel-off mask preparation containing papaya leaf extract to inhibit acne-causing bacteria, namely the bacteria propionibacterium acne. The composition of the peel-off mas…
Beluntas leaves (Pluchea indica L.) is one of the plants that has antibacterial activity such as Propionibacterium acne. Peel-off gel mask is one type of face mask that has advantages in its use, which is easy to remove and lift like an elastic membrane. best. The purpose of this study was to determine the optimum formulation and the best formulation of peel-off gel mask preparations of 4%, 5%,…
Noni fruit (Morinda citrifolia L.) contains several secondary metabolites, one of which is flavonoids. Flavonoids themselves have a special compound, namely quercetin which has the potential as an immunomodulator. Traditional medicinal plants have low solubility in fat and permeability are less able to penetrate the absorption barrier, thus affecting the bioavailability of these natural compoun…