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UJI AKTIVITAS ANTIOSIDAN MIKROALGA SPIRULINA PLATENSIS DENGAN METODE DPPH DAN…
Spirulina platensis contains flavonoids and carotenoids which have pharmacological activity as antioxidants. This study aims to determine the content of phenolic and carotenoid compounds and antioxidant activity contained in Spirulina platensis microalgae using the DPPH (1,1-diphenyl-2-pikrihidrazyl) and FRAP (Ferric-Reducing Antioxidant Power) methods. The content of phenolic compounds obtaine…
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- xviii, 89 hlm.; Ilus.; 29 cm
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- T1056392023
PREPARASI DAN UJI AKTIVITAS ANTIDIABETES SEDIAAN NANOSUSPENSI EKSTRAK DAUN KE…
Daun ketepeng cina diketahui memiliki efek farmakologi sebagai antidiabetes alami dikarenakan mengandung senyawa flavonoid berupa kuarsetin yang mampu menghambat enzim α-glukosidase untuk menurunkan kadar glukosa dalam darah. Efektivitas dan bioavailibilitas ekstrak yang cenderung rendah sehingga dibuat sediaan dengan sistem penghantaran nanopartikel. Penelitian ini bertujuan untuk memformulas…
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- xvii, 121 hlm.; Ilus.; 29 cm
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- T1055772023
FORMULASI DAN ANALISIS MIKROBIOLOGIS LIPSTIK CAIR DENGAN PENGAWET ALAMI CHITO…
Liquid lipstick is a cosmetic type of lip color that is currently in great demand by consumers. Repeated use of liquid lipstick can cause the growth of pathogenic microbes such as Staphylococcus aureus and Candida albicans. Chitooligosaccharide is a derivative of chitosan resulting from the deacetylation of chitin and has been widely reported to have biological activity as an antimicrobial. Thi…
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- xix, 119 hlm.; Ilus.; 29 cm
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- T950142023
UJI AKTIVITAS GASTROPROTEKTIF EKSTRAK ETANOL RIMPANG TEMU IRENG (Curcuma aeru…
Ethanol extract of temu ireng rhizome (Curcuma aeruginosa Roxb.) contains many efficacious secondary metabolites, one of which is flavonoid, phenolic, and curcuminoid. The compound is thought to have the potential to be gastroprotective. This research aimed to determine the effect of differences in the dose of ethanol extract of temu ireng rhizome as gastroprotective on the evaluation parameter…
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- xvii, 106 hlm.; Ilus.; 29 cm
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- T1047642023
AKTIVITAS PREBIOTIK TEPUNG PISANG KEPOK (MUSA PARADISIACA FORMATYPICA) TERHAD…
Kepok banana (Musa paradisiaca formatypica) contains inulin and fructooligosaccharide (FOS) which act as natural prebiotics. This research was conducted to analyze the effect of kepok banana flour before and after modification with high pressure heating on the growth of L. plantarum using Design Expert 12®. Test standardization of the quality of banana flour kepok based on SNI 01-3751-2009. Mo…
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- xvii, 108 hlm.; Ilus.; 29 cm
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- T920912023
FORMULASI DISPERSI PADAT AZITROMISIN DENGAN KITOSAN DAN NATRIUM ALGINAT MENGG…
Azithromycin is a macrolide-derived antibiotic compound that is poorly water soluble. Various technologies are reported to overcome the solubility problem of poorly soluble drugs, one of which is solid dispersion technology. Solid dispersion refers to a group of solid products consisting of at least two different components, generally a hydrophilic matrix and a hydrophobic drug. Solid dispersio…
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- xix, 74 hlm.; Ilus.; 29 cm
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- T1220722023
UJI KADAR FENOLIK TOTAL DAN AKTIVITAS ANTIOKSIDAN SECARA IN-VITRO PADA TANAMA…
Research has been carried out on the anti-oxidant potence of kecombrang (Etlingera elatior), which includes the determination of total phenolic content and antioxidant activity of the extract, and the fractions of the kecombrang (E.elatior) plant. Determination of total phenolic content with gallic acid standard using Follin Ciocalteu reagent. The principle of this test is the formation of a bl…
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- xvii, 115 hlm.; ilus.; 29 cm
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- T891462023
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAN FRAKSI DAUN PUCUK IDAT (Cratoxyl…
Daun pucuk idat mengandung metabolit sekunder yaitu flavonoid, saponin, tanin, triterpenoid, steroid, dan fenolik yang memiliki aktivitas farmakologi sebagai antioksidan. Penelitian ini bertujuan untuk mengetahui karakteristik ekstrak etanol, pengaruh pemberian ekstrak etanol dan fraksi daun pucuk idat terhadap aktivitas antioksidan dengan mengukur kadar MDA, penentuan aktivitas enzim katalase,…
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- xxi, 142 hlm.; ilus.; 29 cm
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- T887122023
PROFIL STRES OKSIDATIF DAN MIKROANATOMI OTAK PEMBERIAN SELF-NANOEMULSIFYING D…
Stres oksidatif dapat menimbulkan kerusakan DNA sehingga dapat menurunkan fungsi kognitif. Katekin pada teh putih memiliki efek farmakologis sebagai antioksidan dapat dijadikan terapi peningkatan fungsi kognitif. Penelitian bertujuan untuk mengetahui nilai profil stres SOD, CAT, dan MDA serta mengetahui gambaran histopatologi hippokampus dan sel neuron. Penelitian menggunakan rancangan post tes…
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- xv, 93 hlm.; ilus.; 29
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- T890102023
PENGARUH PEMBERIAN FRAKSI N-HEKSAN DAUN UBI JALAR UNGU TERHADAP ALIRAN DAN PA…
Daun ubi jalar ungu (Ipomoea Batatas (L.) Lam.) mengandung senyawa beta-karoten yang memiliki efek farmakologis sebagai antiaterosklerosis. Penelitian ini bertujuan untuk melihat aktivitas fraksi n-heksan daun ubi jalar ungu dalam mengembalikan aliran dan faktor koagulasi darah tikus serta pengaruhnya terhadap gambaran histopatologi aorta tikus yang diinduksi suplemen tinggi lemak. Pada penelit…
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- ix, 95 hlm.; ilus.; 29 cm
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- T890962023
UJI AKTIVITAS ANTIOKSIDAN SEDIAAN NANOEMULSI MINYAK BIJI RAMI (Linum usitatis…
Flaxseed oil (Linum usitatissimum) has been shown to enhance the function of the antioxidant system due to its antioxidant compounds such as phenols and vitamin E. The development of flaxseed oil into stable dosage forms such as nanoemulsions is very potential from the point of view of the efficacies contained. This research was conducted to determine the concentration of flaxseed oil in nanoem…
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- xviii, 94 hlm.; ilus.; 29 cm
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- T893412023
UJI AKTIVITAS ANTIOKSIDAN SEDIAAN NANOEMULSI MINYAK SACHA INCHI (Plukenetia v…
Minyak Sacha Inchi (Plukenetia Volubilis L.) mengandung senyawa bioaktif yang bersifat antioksidan diantaranya yaitu flavonoid dan beberapa asam lemak tinggi yakni asam palmitat, asam stearat, asam oleat, asam linoleat, dan asam linolenat. Penelitian ini bertujuan untuk menentukan konsentrasi minyak sacha inchi dalam sediaan nanoemulsi yang memiliki aktivitas antioksidan terbaik kemudian dianal…
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- xvii, 84 hlm.; ilus.; 29 cm
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- T893252023
PENGARUH PEMBERIAN FRAKSI ETIL ASETAT DAUN UBI JALAR UNGU TERHADAP ALIRAN DAN…
Purple sweet potato leaves are plants that contain secondary metabolites of flavonoids, tannins and phenolics which are proven to have activity as a vasodilator and are able to increase the formation of Nitric Oxide (NO) as so as reducing atherosclerosis. The purpose of this study was to determine the effect of giving the ethyl acetate fraction of purple sweet potato leaves on blood flow and bl…
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- iv, 60 hlm.; ilus.; 29 cm
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- T890662023
PENGARUH PEMBERIAN ORALLY DISSOLVING FILM EKSTRAK BUAH MENGKUDU (Morinda citr…
Noni fruit (Morinda citrifolia L.) contains flavonoids that have immunomodulatory activity. Orally Dissolving Film (ODF) formulation removes the bitter taste and low bioavailability of extract. This study aims to determine the characteristics of ODF noni fruit extract and the immunomodulatory effects of ODF noni fruit extract in Wistar male rats induced by E. coli on the number of leukocytes, l…
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- xviii, 135 hlm.; ilus.; 29 cm
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- T1141362023
FORMULASI EKSTRAK DAUN GAMBIR (UNCARIA GAMBIR ROXB.) SEBAGAI KOSMETIK PEMBERS…
Catechins are flavonoid compounds that contain antioxidants that can prevent cell damage from free radicals and reduce excess melanin production by inhibiting the tyrosinase enzyme. Delivery of active substances is more effective when done in dosage forms, so gambir extract is formulated into facial cleansers that can deliver active substances properly. This study aims to obtain an optimum form…
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- xix, 101 hlm.; ilus.; 29 cm
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- T1050322023
PENGARUH PEMBERIAN ORALLY DISSOLVING FILM EKSTRAK DAUN KENIKIR (Cosmos caudat…
Kenikir leaves (Cosmos caudatus. Kunth) contain various secondary metabolic compounds, quercetin which has the potential as an immunomodulator. This study aims to determine number of leukocytes, lymphocytes, neutrophils, monocytes, CD4 T cells, ODF ethanol extract film of kenikir leaves in Wistar rat strain and macroscopic and histopathalogic images of spleen organs. The research used Spektrofo…
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- xviii, 146 hlm.; ilus.; 29 cm
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- T1140462023
OPTIMASI KONSENTRASI TWEEN 80 DAN PEG-400 DALAM SEDIAAN NANOEMULSI DAUN SAMBI…
Sambiloto leaves (Andrographis paniculata (Burm. f.) Wall. Ex Ness) has the potential as a photoprotective agent with a high content of quercetin and andrographolide. The preparation of Sambiloto leaves nanoemulsion was carried out to increase its photoprotective activity and stability. This study aims to determine the optimum concentration of Tween 80 and PEG-400 in the Sambiloto leaves nanoem…
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- xviii, 82 hlm.; ilus.; 29 cm
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- T944682023
EFEK PEMBERIAN SNACK BAR EKSTRAK DAUN PEGAGAN (Centella asiatica L.) KOMBINAS…
Cognitive function improvement is an ability to organize information for the better. One of the methods to improve it is functional food. Gotu kola leaves (Centella asiatica L.) and purple sweet potato (Ipomoea batatas L.) have high antioxidant contents of flavanoid, asiaticoside, triterpenoid, and anthocyanin compounds which are able to counteract free radicals. This research aims at determini…
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- xx, 91 hlm.; ilus.; 29 cm
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- T888232023
AKTIVITAS ANTIINFLAMASI TRANSDERMAL PATCH EKSTRAK DAUN MELINJO (Gnetum gnemon…
Inflammation can cause an uncomfortable response due to pain. Plants that can be used as anti-inflammatory come from melinjo leaf at dose of 563 mg/kg BB. Delivering the active substance is carried out as a transdermal patch. The use of plasticizers can improve the mechanical properties of patch preparations. This study aims to obtain the best formula for transdermal patch preparations for anti…
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- xvii, 102 hlm.; ilus.; 29 cm
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- T949402023
EFEK PEMBERIAN SELF-NANO EMULSION EKSTRAK WHITE TEA TERHADAP PROFIL INSULIN, …
White tea contains catechins which have pharmacological effects as antioxidants. This study used test animals in the form of male Wistar rats which were divided into seven groups: normal group, negative control (STZ-NA induced), positive control (STZ-NA and Glibenclamide induced), group 1 (STZ-NA induced and SNE base). , Group 2 (induced STZ-NA and SNE-white tea extract), group 3 (induced STZ-N…
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- xvii, 125 hlm.; ilus.; 29 cm
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- T889302023
UJI EFEK ANALGETIK EKSTRAK ETANOL DAUN SUNGKAI (Peronema canescens Jack) PADA…
Pain is a sign that something wrong in the body system such as tissue problem, also it is one of the most complaints when patient sees doctor. Pain can be treated with analgesic drug. One of plant which is widely used as an herbal medicine is Peronema canescens. The leaves of P. canescens has been reported contained betulinic acid, glycoside, β-sitosterol, stigmaterol and phytol. The aims of t…
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- x, 128 hlm.; ilus.; 29 cm
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- T892992023
OPTIMASI DAN KARAKTERISASI FORMULA TRANSFERSOM KLINDAMISIN HCL DENGAN VARIASI…
Sediaan semisolida klindamisin HCl cenderung sulit menembus stratum korneum kulit sehingga diperkirakan hanya sekitar 5-8% zat aktif yang dapat sampai ke reseptor. Untuk mengatasi hal ini, diformulasikan klindamisin HCl dalam sistem pembawa transfersom yang terdiri dari struktur lipid bilayer yang dapat menjerap klindamisin HCl dengan baik sehingga akan menaikkan membantu klindamisin HCl menemb…
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- xvii, 88 hlm.; ilus.; 29 cm
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- T891752023
APLIKASI FULL FACTORIAL DESIGN 2^3 PADA OPTIMASI PROSES EKSTRAKSI KULIT BUAH …
Senyawa flavonoid antosianin pada kulit buah kopi robusta mempunyai aktivitas antioksidan yang tinggi. Penelitian ini bertujuan untuk mengetahui hasil proses optimasi ekstrak kulit buah kopi robusta menggunakan full factorial design serta karakteristik ekstrak optimal. Metode ekstraksi yang digunakan berupa ultrasound-Assisted Extraction (UAE) dan dianalisis dengan full factorial design 23 (FFD…
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- xvii, 120 hlm.; ilus.; 29 cm
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- T890182023
EFEK PEMBERIAN SNACK BAR EKSTRAK DAUN PEGAGAN (Centella asiatica L.) KOMBINAS…
Gotu Kola ( Centella asiatica ) and cocoa ( Theobroma cacao L. ) one of the plants believed to have many benefits. The High antioxidant content, especially flavonoids, triterpenoids, polyphenols, saponins from gotu kola and cocoa beans are believed to increase memory or improve memory. This study aims to determine levels of flavonoids, levels of proximate characteristics of Snack bars , and to …
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- xviii, 95 hlm.; ilus.; 29 cm
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- T888482023
OPTIMASI DAN KARAKTERISASI PATCH TRANSDERMAL EKSTRAK ETIL ASETAT DAUN GAMBIR …
Ekstrak daun gambir mengandung berbagai senyawa metabolit sekunder salah satunya flavonoid. Flavonoid sendiri memiliki berpotensi sebaagai analgetik dan antiinflasmasi. Proses penghantaran zat aktif ini akan lebih efektif apabila dilakukan dalam bentuk suatu sediaan. Salah satu bentuk sediaan tersebut adalah patch transdermal. Komponen penting pada sediaan patch adalah polimer sehingga pada pen…
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- xix, 139n hlm.; ilus.; 29 cm
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- T889702023
UJI AKTIVITAS ANALGETIK EKSTRAK ETANOL DAUN SEMPRAWANG (Dillenia ochreata) PA…
The ethanol extract of Dillenia ochreata leaves contains secondary metabolites such as triterpenoids, steroids, phenolics and flavonoids which have potential as analgesics with the ability to inhibit prostaglandins as the main mediators of pain. The aims of this study to determine the best dose of the ethanol extract from D. ochreata leaves through the hot plate test, to determine the location …
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- xvii, 107 hlm.; ilus.; 29 cm
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- T892922023
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAN FRAKSI DAUN BALIK ANGIN (MALLOTU…
One of the plants that has the potential as a natural antioxidant is balik angin plant (Mallotus paniculatus (Lam.) Mull. Arg.). Based on the results of the phytochemical screening, the leaves of balik angin contain flavonoids, steroids, triterpenoids, saponins, tannins and phenolics. This study was aimed to determine the characteristics of the extract and the antioxidant activity of the ethano…
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- xix, 118 hlm.; ilus.; 29 cm
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- T911652023
HUBUNGAN ANTARA PERILAKU MENGKONSUMSI ASAM FOLAT DENGAN KADAR ASAM FOLAT SERU…
Kesehatan ibu hamil sangat mempengaruhi kehidupan janin. Untuk melahirkan bayi yang sehat ibu hamil perlu mempunyai kesehatan yang optimal. Penelitian ini bertujuan untuk menganalisis perilaku ibu hamil dalam mengkonsumsi asam folat dengan kadar asam folat serum di Kabupaten Seluma. Metode penelitian yang digunakan yaitu penelitian analitik dengan desain cross-sectional. Penelitian ini dilakuka…
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- xviii, 86 hlm.; ilus.; 29 cm
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- T1127602023
EFEK INHIBISI ENZIM XANTIN OKSIDASE EKSTRAK DAN FRAKSI POLAR ETIL ASETAT DAUN…
Introduction: Hyperuricemia is a condition where uric acid levels are above normal levels (> 7 mg/dL in women and > 6 mg/dL in men) and can cause negative impact on a person's body if left untreated. Long term hyperuricemia will lead to gout arthritis, kidney stones and increase risk factor of hyperlipidemia, diabetes, hypertension and other cardiovascular diseases. So far, allopurinol is the f…
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- xix, 109 hlm.; ilus.; 29 cm
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- T845612023
UJI DAYA ANTIBAKTERI EKSTRAK ETANOL RAMBUT JAGUNG (ZEA MAYS SACCHARATA STURT)…
Background: Periodontal disease is the second most frequent dental and oral health problem In Indonesia. Porphyromonas gingivalis, prevalent in subgingival plaques, is the primary bacteria that cause periodontal disease. Periodontal disease can be prevented mechanically, chemically, or spontaneously by inhibiting plaque growth. Natural ingredients such as corn hair, which include antibacterial …
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- xiv, 39 hlm.; ilus.; 29 cm
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- T711562022
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